Dahal Sumit, Ghimire Dipesh K C, Sapkota Saroj, Dahal Suyash, Kafle Paritosh, Bhandari Manjul
Interfaith Medical Center, Brooklyn, NY, USA.
KIST Medical College and Teaching Hospital, Lalitpur, Nepal.
J Investig Med High Impact Case Rep. 2018 May 2;6:2324709618773789. doi: 10.1177/2324709618773789. eCollection 2018 Jan-Dec.
Renal and neurological involvements are frequently seen in thrombotic thrombocytopenic purpura (TTP). Cardiac involvement, however, has been rarely reported. In this article, we present 2 cases of myocardial infarction in patients with TTP. In the first case, a young man presented with non-ST-segment elevation myocardial infarction that resolved promptly with plasmapheresis. The second patient developed ST-segment elevation myocardial infarction early in the course of the disease and died before plasmapheresis could be initiated. Hence, a high degree of suspicion with prompt diagnosis and treatment is needed to prevent mortality associated with cardiac involvement in TTP.
肾脏和神经系统受累在血栓性血小板减少性紫癜（TTP）中较为常见。然而，心脏受累的报道却很少。在本文中，我们介绍了2例TTP患者发生心肌梗死的病例。第一例，一名年轻男性表现为非ST段抬高型心肌梗死，经血浆置换后迅速缓解。第二例患者在疾病早期发生ST段抬高型心肌梗死，在能够开始血浆置换之前死亡。因此，需要高度怀疑并及时诊断和治疗，以预防TTP患者因心脏受累而导致的死亡。
