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一名患有囊性纤维化的青少年意外身高降低

Unexpected Height Loss in an Adolescent With Cystic Fibrosis.

作者信息

Schendel Anne, Mai Jillian, Espinosa Rachel, Tomcyzk Carlye T, Laguna Theresa A

机构信息

University of Minnesota, Minneapolis, MN, USA.

University of Minnesota Masonic Children's Hospital, Minneapolis, MN, USA.

出版信息

Glob Pediatr Health. 2018 May 7;5:2333794X18773662. doi: 10.1177/2333794X18773662. eCollection 2018.

DOI:10.1177/2333794X18773662
PMID:29761141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5946352/
Abstract

This case report describes an adolescent with pancreatic insufficient cystic fibrosis, malnutrition, and cystic fibrosis-related diabetes found to have a loss in height at a routine outpatient clinic visit. He was subsequently admitted to the hospital for treatment of a pulmonary exacerbation and was found to have multiple, nontraumatic vertebral compression fractures. This report emphasizes the importance of routine review of growth charts and aggressive treatment of vitamin deficiencies and malnutrition in people with cystic fibrosis.

摘要

本病例报告描述了一名患有胰腺功能不全的囊性纤维化、营养不良及囊性纤维化相关糖尿病的青少年,在一次常规门诊就诊时发现身高下降。随后他因肺部病情加重入院治疗,结果发现有多处非创伤性椎体压缩性骨折。本报告强调了对囊性纤维化患者常规检查生长图表以及积极治疗维生素缺乏和营养不良的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ad/5946352/9d5ba0baa0bf/10.1177_2333794X18773662-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ad/5946352/ed1e84c7be7f/10.1177_2333794X18773662-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ad/5946352/9d5ba0baa0bf/10.1177_2333794X18773662-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ad/5946352/ed1e84c7be7f/10.1177_2333794X18773662-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ad/5946352/9d5ba0baa0bf/10.1177_2333794X18773662-fig2.jpg

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引用本文的文献

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本文引用的文献

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Bone health and disease in cystic fibrosis.囊性纤维化中的骨骼健康与疾病
Paediatr Respir Rev. 2016 Aug;20 Suppl:2-5. doi: 10.1016/j.prrv.2016.06.003. Epub 2016 Jun 21.
2
Multiple prevalent fractures in relation to macroscopic bone architecture in patients with cystic fibrosis.囊性纤维化患者与宏观骨结构相关的多处常见骨折。
J Cyst Fibros. 2018 Jan;17(1):114-120. doi: 10.1016/j.jcf.2016.06.004. Epub 2016 Jun 18.
3
Trabecular and cortical bone deficits are present in children and adolescents with cystic fibrosis.患有囊性纤维化的儿童和青少年存在小梁骨和皮质骨缺损。
Bone. 2016 Sep;90:7-14. doi: 10.1016/j.bone.2016.04.030. Epub 2016 Apr 29.
4
Factors associated with low bone mineral density in patients with cystic fibrosis.囊性纤维化患者骨矿物质密度低的相关因素。
J Bone Miner Metab. 2015 Mar;33(2):180-5. doi: 10.1007/s00774-014-0572-z. Epub 2014 Mar 16.
5
Single high-dose oral vitamin D3 (stoss) therapy--a solution to vitamin D deficiency in children with cystic fibrosis?单剂量大剂量口服维生素 D3(冲击疗法)——囊性纤维化患儿维生素 D 缺乏的解决方案?
J Cyst Fibros. 2013 Mar;12(2):177-82. doi: 10.1016/j.jcf.2012.08.007. Epub 2012 Sep 19.
6
Diabetes mellitus and bone disease in cystic fibrosis.囊性纤维化中的糖尿病与骨病
Semin Respir Crit Care Med. 2009 Oct;30(5):514-30. doi: 10.1055/s-0029-1238910. Epub 2009 Sep 16.
7
Multiple vertebral compression fractures in a patient treated with corticosteroids for cystic fibrosis.一名接受皮质类固醇治疗囊性纤维化的患者发生多处椎体压缩性骨折。
Can J Surg. 2002 Oct;45(5):383-4.