Kubar' O I, Shvetsova E G, Zlydnikov D M
Ter Arkh. 1988;60(8):66-8.
Long-term experience in the clinical and epidemiological testing of antiinfluenzal drugs made it possible to derive major principles of their practical application. A study of the therapeutic and prophylactic efficacy of antiinfluenzal drugs has demonstrated convincingly that success of testing depends on the onset of treatment and epidemiological substantiation of drug administration. The observance of these conditions provides a social, medical and economic effect. Practical implementation of the results obtained required the identification of risk groups of developing influenza and other ARVI, the expansion of a network of rapid diagnostic laboratories, early emergency prevention with maximum coverage of high risk groups, and early administration of antiinfluenzal drugs distributed free of charge.
在抗流感药物的临床和流行病学测试方面的长期经验，使得得出其实际应用的主要原则成为可能。对抗流感药物治疗和预防效果的研究令人信服地表明，测试的成功取决于治疗开始时间和药物给药的流行病学依据。遵守这些条件可带来社会、医学和经济效益。要实际应用所获得的结果，需要确定发生流感和其他急性呼吸道病毒感染的风险群体，扩大快速诊断实验室网络，对高风险群体进行最大程度覆盖的早期应急预防，并尽早免费发放抗流感药物。
