Wen B H, Cheng J L, Zhang H X, Zhang Z X, Wang F F, Xue K K
Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhonghua Yi Xue Za Zhi. 2018 May 8;98(17):1347-1351. doi: 10.3760/cma.j.issn.0376-2491.2018.17.013.
To investigate the diagnostic value of RESOLVE DWI in the evaluation of benign and malignant epithelial tumors of parotid gland. A total of 106 patients in the First Affiliated Hospital of Zhengzhou University with epithelial tumors of parotid gland confirmed by pathology from July 2015 to October 2017 were retrospectively analyzed. All patients underwent preoperative routine MRI and RESOLVE DWI, the ADC average values were calculated, test were used to compare the ADC values of benign and malignant epithelial tumors of parotid gland. Diagnostic performance of ADC value was compared using receiver operating characteristic (ROC)curves. All lesions were solitary, including 69 benign epithelial tumors and 37 malignant epithelial tumors. The mean ADC values of pleomorphic adenoma and basal cell adenoma, adenolymphoma and malignant epithelial tumors were (1.47±0.16)×10(-3) mm(2)/s, (0.83±0.19)×10(-3) mm(2)/s and(1.14±0.14)×10(-3) mm(2)/s, the mean ADC value of adenolymphoma lower than the rest of the two groups, there were statistically significant differences among them (<0.05). Using 0.94×10(-3) mm(2)/s≤ADC value≤1.28×10(-3)mm(2)/s as the critical value for diagnosing malignant epithelial tumors of parotid gland and comparing with pathological results, the result obtained had a sensitivity of 81.1%, specificity of 88.9%. ADC value had high correlations compared with pathological results, value was 0.600. RESOLVE DWI can be applied in differential diagnosis between benign and malignant epithelial tumors of parotid gland.
探讨RESOLVE DWI在腮腺上皮性良恶性肿瘤评估中的诊断价值。回顾性分析2015年7月至2017年10月郑州大学第一附属医院106例经病理确诊的腮腺上皮性肿瘤患者。所有患者术前行常规MRI及RESOLVE DWI检查，计算ADC平均值，采用检验比较腮腺上皮性良恶性肿瘤的ADC值。利用受试者工作特征（ROC）曲线比较ADC值的诊断效能。所有病变均为单发，其中良性上皮性肿瘤69例，恶性上皮性肿瘤37例。多形性腺瘤、基底细胞腺瘤、腺淋巴瘤及恶性上皮性肿瘤的平均ADC值分别为（1.47±0.16）×10⁻³mm²/s、（0.83±0.19）×10⁻³mm²/s和（1.14±0.14）×10⁻³mm²/s，腺淋巴瘤的平均ADC值低于其余两组，差异有统计学意义（<0.05）。以0.94×10⁻³mm²/s≤ADC值≤1.28×10⁻³mm²/s作为诊断腮腺恶性上皮性肿瘤的临界值并与病理结果比较，结果显示敏感性为81.1%，特异性为88.9%。ADC值与病理结果具有高度相关性，相关系数为0.600。RESOLVE DWI可应用于腮腺上皮性良恶性肿瘤的鉴别诊断。
