Lajzová Sylva, Kroupa Radek, Buliková Alena, Bohatá Šárka, Packová Barbora, Šenkyřík Michal
Vnitr Lek. 2018 Spring;64(3):272-279.
Splanchnic vein thrombosis (SVT) represents an unusual manifestation of venous thromboembolism. The etiological factors for SVT can be divided into local and systemic, frequently found concurrently. SVT can be the first presenting symptom in myeloproliferative neoplasms. SVT puts the patients affected in jeopardy of developing the intestinal infarction, impairing the liver function and portal hypertension development with the risk of potentially life-threatening gastrointestinal bleeding. The current guidelines emphasise the role of anticoagulation in acute splanchnic thrombosis. Considering the potentially fatal complications it is necessary to tailor the anticoagulant treatment individually. The duration of anticoagulant therapy is strongly dependent upon the risk evaluation of thrombosis recurrence. The article deals with the causes, diagnostic methods and aspects influencing the therapeutic strategy.Key words: anticoagulation - liver cirrhosis - portal hypertension - prothrombotic state - splanchnic vein thrombosis.
内脏静脉血栓形成(SVT)是静脉血栓栓塞的一种罕见表现。SVT的病因可分为局部和全身因素,且常常同时存在。SVT可能是骨髓增殖性肿瘤的首发症状。SVT会使患者面临发生肠梗死、肝功能损害以及门静脉高压进而导致危及生命的胃肠道出血的风险。当前指南强调抗凝在急性内脏血栓形成中的作用。鉴于其潜在的致命并发症,有必要进行个体化的抗凝治疗。抗凝治疗的持续时间很大程度上取决于血栓复发的风险评估。本文探讨了其病因、诊断方法以及影响治疗策略的相关方面。关键词:抗凝 - 肝硬化 - 门静脉高压 - 血栓前状态 - 内脏静脉血栓形成