Kaymaz Cihangir, Akbal Ozgur Yasar, Hakgor Aykun, Tokgoz Hacer Ceren, Tanyeri Seda
University of Health Sciences, Kosuyolu Heart Education and Research Hospital Cevizli Mah., İstanbul, Turkey.
Pulm Circ. 2018 Jul-Sep;8(3):2045894018780522. doi: 10.1177/2045894018780522. Epub 2018 May 16.
Despite the significant mortality and mobidity benefits being obtained with the targeted therapies in patients with pulmonary arterial hypertension (PAH), mid- to long-term survival of patients with this disease has remained unsatisfactory. For earlier and reliable risk stratification in PAH and tailoring the dynamic management strategies, various risk assessment models have been developed. Currently available risk reduction strategy recommended by the European Society of Cardiology (ESC)/European Respiratory Society (ERS) 2015 Pulmonary Hypertension Guidelines has been utilized in three recent registries. In this review, we evaluated the risk prediction models and management algorithms in this setting and propose an alternative parametric display, a bull's eye, dart table scheme for ESC/ERS goal-orientated risk reduction strategy in patients with PAH.
尽管靶向治疗给肺动脉高压（PAH）患者带来了显著的死亡率和发病率改善，但该疾病患者的中长期生存率仍不尽人意。为了对PAH进行早期且可靠的风险分层并制定动态管理策略，人们开发了各种风险评估模型。欧洲心脏病学会（ESC）/欧洲呼吸学会（ERS）2015年肺动脉高压指南推荐的现有风险降低策略已在最近的三个登记研究中得到应用。在本综述中，我们评估了这种情况下的风险预测模型和管理算法，并提出了一种替代的参数显示方法，即靶心、飞镖表方案，用于PAH患者ESC/ERS目标导向的风险降低策略。
