HIV/AIDS门诊患者低白蛋白血症的患病率
Prevalence of hypoalbuminemia in outpatients with HIV/AIDS.
作者信息
Leal José Adalberto, Fausto Maria Arlene, Carneiro Mariângela, Tubinambás Unaí
机构信息
Programa de Pós-Graduação em Doenças Infecciosas e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
Departamento de Alimentos, Escola de Nutrição, Universidade Federal de Ouro Preto, Ouro Preto, MG, Brasil.
出版信息
Rev Soc Bras Med Trop. 2018 Mar-Apr;51(2):203-206. doi: 10.1590/0037-8682-0093-2017.
INTRODUCTION
Hypoalbuminemia may predict progression of disease and mortality in patients with human immunodeficiency virus (HIV) infection/acquired immune deficiency syndrome (AIDS). This study was conducted to investigate the risk factors associated with hypoalbuminemia in outpatients with HIV/AIDS.
METHODS
A cross-sectional study was performed in 196 outpatients with HIV/AIDS.
RESULTS
The prevalence of hypoalbuminemia was 11.7%. The only risk factor associated with hypoalbuminemia was current antiretroviral therapy (no exposure: odds ratio=3.46, 95% confidence interval=1.20-10.02).
CONCLUSIONS
The monitoring of plasma albumin is key to determine when antiretroviral therapy should be initiated in individuals not exposed to antiretroviral medicines.
引言
低白蛋白血症可能预示着人类免疫缺陷病毒（HIV）感染/获得性免疫缺陷综合征（AIDS）患者的疾病进展和死亡率。本研究旨在调查HIV/AIDS门诊患者低白蛋白血症的相关危险因素。
方法
对196例HIV/AIDS门诊患者进行了横断面研究。
结果
低白蛋白血症的患病率为11.7%。与低白蛋白血症相关的唯一危险因素是当前的抗逆转录病毒治疗（未接受治疗：比值比=3.46，95%置信区间=1.20-10.02）。
结论
对于未接受抗逆转录病毒药物治疗的个体，监测血浆白蛋白是确定何时开始抗逆转录病毒治疗的关键。
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