Nayak Gyanaranjan, Virk Ramandeep S, Singh Manvi, Singh Meenu
Departments of Otolaryngology, Head and Neck Surgery.
Pediatric Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Bronchology Interv Pulmonol. 2018 Oct;25(4):343-345. doi: 10.1097/LBR.0000000000000507.
Nasogastric tubes have been used in the pediatric age group to supplement nutrition in cases of malignancy and failure to thrive due to a variety of causes. Breathing difficulty may occur after the insertion of a nasogastric tube and it can have multiple causes. Here we discuss 2 patients of acute lymphoblastic leukemia (ALL) who developed a rare condition called the Sofferman syndrome (nasogastric tube syndrome). We will also briefly outline a diagnostic algorithm to facilitate its fast and correct diagnosis.
We present 2 cases of pediatric ALL who were undergoing chemotherapy in the pediatrics department. They presented with respiratory distress and stridor within a few days of nasogastric tube insertion.
Two cases of ALL developed stridor within 48 hours of nasogastric tube insertion. The stridor gradually progressed over days. Both the patients required tracheostomy to secure the airway. Removal of the nasogastric tube did not reverse the airway obstruction.
Nasogastric tube syndrome is a potentially life-threatening condition and has to be considered as a possibility in immune-compromised patients who present with voice change and stridor after nasogastric tube insertion.
鼻胃管已被用于儿科患者群体，以补充因各种原因导致的恶性肿瘤及发育不良情况下的营养。插入鼻胃管后可能会出现呼吸困难，其原因可能多种多样。在此，我们讨论2例急性淋巴细胞白血病（ALL）患者，他们患上了一种罕见病症，即索弗曼综合征（鼻胃管综合征）。我们还将简要概述一种诊断算法，以促进其快速、准确的诊断。
我们介绍2例在儿科接受化疗的小儿ALL患者。他们在插入鼻胃管后的几天内出现呼吸窘迫和喘鸣。
2例ALL患者在插入鼻胃管后48小时内出现喘鸣。喘鸣在数天内逐渐加重。两名患者均需要气管切开以确保气道安全。拔除鼻胃管并未逆转气道阻塞。
鼻胃管综合征是一种潜在的危及生命的病症，对于在插入鼻胃管后出现声音改变和喘鸣的免疫功能低下患者，必须考虑到这种可能性。
