Trendafilova Antoaneta, Todorova Milka, Genova Victoria, Peter Samuel, Wolfram Evelyn, Danova Kalina, Evstatieva Luba
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria.
Institute of Chemistry and Biotechnology, Zurich University of Applied Sciences, 8820, Wädenswil, Switzerland.
Chem Biodivers. 2018 Jul;15(7):e1800109. doi: 10.1002/cbdv.201800109. Epub 2018 Jun 11.
The aim of this study was to evaluate flower and leaf methanol extracts of Artemisia alba Turra for their total phenolic and flavonoid contents, antioxidant capacity and to investigate their phenolic composition. The flower extract was richer in total phenolics and flavonoids and possessed higher antioxidant activity through DPPH and ABTS assays. The UHPLC-PDA-MS analysis of the flower and leaf methanol extracts revealed similar phenolic profile and allowed identification of 31 phenolic compounds (flavonoids, coumarins, and phenolic acids) by comparison with the respective reference compounds or tentatively characterized by their chromatographic behavior, UV patterns, and MS fragmentations. The presence of hispidulin, jaceosidin, desmethoxycentaureidin, and dicaffeoyl esters of quinic acid in A. alba is reported herein for the first time. The distribution of flavonoids in A. alba from different origins was discussed from chemotaxonomic point of view.
本研究的目的是评估白蒿的花和叶甲醇提取物的总酚和黄酮含量、抗氧化能力，并研究其酚类成分。通过DPPH和ABTS分析，花提取物的总酚和黄酮含量更高，抗氧化活性更强。花和叶甲醇提取物的超高效液相色谱-光电二极管阵列-质谱分析显示出相似的酚类谱图，并通过与各自的参考化合物比较或根据其色谱行为、紫外图谱和质谱裂解对31种酚类化合物（黄酮类、香豆素类和酚酸类）进行了鉴定。本文首次报道了白蒿中含有棉蓟素、紫菀苷、去甲氧基矢车菊素和奎宁酸的二咖啡酰酯。从化学分类学的角度讨论了不同来源的白蒿中黄酮类化合物的分布。
