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以社区样本为参照的自杀受害者一生中首次及后续酗酒与精神障碍情况——伦德贝研究(1947 - 1997年)

First and Subsequent Lifetime Alcoholism and Mental Disorders in Suicide Victims With Reference to a Community Sample-the Lundby Study 1947-1997.

作者信息

Holmstrand Cecilia, Bogren Mats, Mattisson Cecilia, Brådvik Louise

机构信息

Division of Psychiatry, Department of Clinical Sciences, Skåne University Hospital, University of Lund, Lund, Sweden.

出版信息

Front Psychiatry. 2018 May 3;9:173. doi: 10.3389/fpsyt.2018.00173. eCollection 2018.

Abstract

Suicide victims have been found to frequently suffer from mental disorders, often more than one, and comorbidity has also been found to be a risk factor for suicide. The aim of the present study was to determine the first disorder and possible subsequent disorders in suicide victims during their lifetimes and to compare their development with the development of mental and alcohol use disorders (AUDs) in a community sample. The Lundby Study is a prospective longitudinal study of mental health in a general population comprising 3,563 subjects, including 68 suicide victims, followed by four field investigations from 1947 to 1997; mortality was monitored up to 2011. AUD was most common as a first diagnosis (26/68, 38.2%) among suicide victims, followed by "depression" (20/68, 29.4%) and "anxiety" (7/68, 10.3%). A predominance of AUD as a first diagnosis was found in the male group, whereas "depression" was the most common first diagnosis in the female group. However, there were very few females with AUD in the Lundby Study. In the whole population, it was more common for someone who started with an AUD to develop a subsequent mental disorder than the other way around. The same was true for AUD in relation to depression. AUD was the most common first mental disorder among male suicide victims and could thus be considered a starting point in the suicidal process. We propose that in addition to detecting and treating depression, it is important to detect and treat AUD vigorously and to be alert for subsequent symptoms of depressive and other mental disorders in suicide prevention efforts.

摘要

已发现自杀受害者经常患有精神障碍,往往不止一种,而且共病也被发现是自杀的一个风险因素。本研究的目的是确定自杀受害者一生中的首发障碍以及可能随后出现的障碍,并将其发展情况与社区样本中精神障碍和酒精使用障碍(AUDs)的发展情况进行比较。伦德比研究是一项对普通人群心理健康的前瞻性纵向研究,包括3563名受试者,其中有68名自杀受害者,从1947年到1997年进行了四次实地调查;对死亡率的监测一直持续到2011年。在自杀受害者中,AUD作为首发诊断最为常见(26/68,38.2%),其次是“抑郁症”(20/68,29.4%)和“焦虑症”(7/68,10.3%)。在男性组中,AUD作为首发诊断占主导地位,而在女性组中,“抑郁症”是最常见的首发诊断。然而,在伦德比研究中,患有AUD的女性很少。在整个人口中,以AUD开始的人随后发展为精神障碍的情况比相反的情况更常见。AUD与抑郁症的关系也是如此。AUD是男性自杀受害者中最常见的首发精神障碍,因此可被视为自杀过程的一个起点。我们建议,在自杀预防工作中,除了检测和治疗抑郁症外,大力检测和治疗AUD并警惕抑郁和其他精神障碍的后续症状也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db1b/5943570/dd394dedbc2c/fpsyt-09-00173-g0001.jpg

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