小肠和阑尾肿瘤的分子诊断：2018年更新

Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix: 2018 Update.

作者信息

Zhang Yingtao, Zulfiqar Muhammad, Bluth Martin H, Bhalla Amarpreet, Beydoun Rafic

机构信息

PGY-3 Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo General Hospital, A-701, 100 High Street, Buffalo, NY 14203, USA.

Southeastern Pathology Associates (SEPA Labs), 203 Indigo Drive, Brunswick, GA 31525, USA.

出版信息

Clin Lab Med. 2018 Jun;38(2):343-355. doi: 10.1016/j.cll.2018.03.002.

DOI:10.1016/j.cll.2018.03.002

PMID:29776634

Abstract

Neoplasms of the small intestine are rare in comparison with colorectal tumors. The most common tumor types arising in the small intestine are adenocarcinomas, well-differentiated neuroendocrine tumors, gastrointestinal stromal tumors, and lymphoma. Primary appendiceal neoplasms are rare and found in less than 2% of appendectomy specimens with an incidence of approximately 1.2 cases per 100,000 people per year in the United States. This article explores molecular diagnostics in the neoplasms of small intestine and appendix.

摘要

与结直肠肿瘤相比，小肠肿瘤较为罕见。小肠中最常见的肿瘤类型是腺癌、高分化神经内分泌肿瘤、胃肠道间质瘤和淋巴瘤。原发性阑尾肿瘤很罕见，在阑尾切除标本中不到2%，在美国，每年的发病率约为每10万人中有1.2例。本文探讨小肠和阑尾肿瘤的分子诊断。