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回顾性分析及文献复习:阑尾肿瘤性黏液性病变

A retrospective analysis and literature review of neoplastic appendiceal mucinous lesions.

机构信息

Surgery Department, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, 28005, Spain.

Pathology Department, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, 28805, Spain.

出版信息

BMC Surg. 2021 Feb 11;21(1):79. doi: 10.1186/s12893-021-01091-9.

Abstract

BACKGROUND

At present, the term mucocele is outdated, and mucinous appendiceal neoplasm is preferred. Mucinous appendiceal neoplasm is an uncommon pathology that occurs predominantly in middle-aged women. Its classification and management have been the subject of debate in recent decades. The aim of this study was to analyse the incidence, clinical management and survival of these tumours diagnosed in our centre in the last 10 years.

METHODS

This was a retrospective observational study of patients with a diagnosis of appendiceal neoplasms between 2009 and 2018 in our centre. Variables such as sex, age, tumour type, clinical status, diagnosis, treatment and survival were collected. All data were analysed using the statistical program IBM SPSS Statistic® version 25.

RESULTS

Twenty-nine patients with a diagnosis of appendiceal neoplasm were identified, and 24 corresponded to neoplastic appendiceal mucinous lesions (85.7%). The average age was 59.7 ± 17.6 years. Most patients were women (15 cases; 62.5%). Most of them presented with chronic abdominal pain (37.5%), and the diagnosis was performed by computed tomography (CT) (50%). The treatment was surgical in all cases. The surgical technique depended on the findings and histology of the tumour.

CONCLUSION

Mucinous appendiceal neoplasms are an uncommon entity, and their pathological classification and management have recently changed.

摘要

背景

目前,“黏液囊肿”这一术语已经过时,“黏附性阑尾肿瘤”更为恰当。黏附性阑尾肿瘤是一种罕见的病理学表现,主要发生于中年女性。近几十年来,其分类和处理一直是争论的主题。本研究旨在分析过去 10 年来本中心诊断的此类肿瘤的发病率、临床管理和生存情况。

方法

这是一项回顾性观察性研究,研究对象为 2009 年至 2018 年在本中心诊断为阑尾肿瘤的患者。收集了性别、年龄、肿瘤类型、临床状况、诊断、治疗和生存等变量。所有数据均使用 IBM SPSS Statistic® 版本 25 统计程序进行分析。

结果

共发现 29 例阑尾肿瘤患者,其中 24 例为黏附性阑尾肿瘤(85.7%)。平均年龄为 59.7±17.6 岁。大多数患者为女性(15 例;62.5%)。她们大多表现为慢性腹痛(37.5%),诊断方法为计算机断层扫描(CT)(50%)。所有病例均采用手术治疗。手术技术取决于肿瘤的发现和组织学。

结论

黏附性阑尾肿瘤是一种罕见实体,其病理分类和处理方法近来发生了变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c517/7877070/8a7ae6647ca6/12893_2021_1091_Fig1_HTML.jpg

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