Al-Janabi Yusra, Al-Janabi Khalid, Tzafetta Kallirroi, Petkar Mahir
St Andrews Centre for Plastic Surgery and Burns, Mid Essex Hospital Services NHS Trust, Chelmsford, UK.
Histopathology Department, Mid Essex Hospital Services NHS Trust, Chelmsford, UK.
BMJ Case Rep. 2018 May 18;2018:bcr-2017-222641. doi: 10.1136/bcr-2017-222641.
Primary cutaneous extraskeletal osteosarcoma (PCEO) is a rare malignant neoplasm with less than 20 cases reported in the literature to date. Presenting as a nodule or mass on the skin, commonly at sites of previous trauma or radiation, these lesions are differentiated from other neoplasms through their characteristic microscopic appearance. This report highlights a case of PCEO in a 75-year-old man with a history of squamous cell carcinoma (SCC) of the scalp. Histological examination of a scalp nodule in the region of a previously excised SCC revealed proliferation of osteoid surrounded by malignant osteocytes. An overview of this condition and differential diagnoses are presented in this report.
原发性皮肤骨外骨肉瘤（PCEO）是一种罕见的恶性肿瘤，迄今为止文献报道的病例不足20例。这些病变表现为皮肤上的结节或肿块，常见于既往创伤或放疗部位，通过其特征性的显微镜表现与其他肿瘤相鉴别。本报告重点介绍了一名75岁男性的PCEO病例，该患者有头皮鳞状细胞癌（SCC）病史。对先前切除的SCC区域的头皮结节进行组织学检查，发现类骨质增生，周围有恶性骨细胞。本报告介绍了这种疾病的概述和鉴别诊断。
