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接受与承诺疗法预防高危退伍军人慢性术后疼痛和阿片类药物使用:一项初步随机对照研究。

Acceptance and Commitment Therapy for Prevention of Chronic Postsurgical Pain and Opioid Use in At-Risk Veterans: A Pilot Randomized Controlled Study.

机构信息

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas; Center for Innovations, Quality, and Effectiveness, Michael E. Debakey Veterans Affairs Medical Center, Houston, Texas.

College of Public Health, University of Iowa, Iowa City, Iowa.

出版信息

J Pain. 2018 Oct;19(10):1211-1221. doi: 10.1016/j.jpain.2018.04.016. Epub 2018 May 17.

Abstract

UNLABELLED

High levels of pain, significant anxiety, or depressive symptoms before surgery put patients at elevated risk for chronic pain and prolonged opioid use following surgery. The purpose of this preliminary study was to assess the efficacy of a 1-day Acceptance and Commitment Therapy (ACT) workshop in "at-risk" veterans for the prevention of chronic pain and opioid use following orthopedic surgery. In a randomized controlled trial, 88 at-risk veterans undergoing orthopedic surgery were assigned to treatment as usual (TAU; n = 44) or TAU plus a 1-day ACT workshop (n = 44). Pain levels and opioid use were assessed up to 3 months following surgery. Pain acceptance and values-based behavior were assessed at baseline and 3-month follow-up. Participants who completed the ACT workshop reached pain and opioid cessation sooner than those in TAU. Postoperative complications exhibited a moderating effect on these outcomes, such that the effects of ACT were greater in patients without complications. Increases in pain acceptance and values-based behavior, processes targeted in ACT, were related to better outcomes. These promising results merit further investigation in a larger clinical trial. Providing an intervention before surgery for at-risk veterans has the potential to change clinical practice from a focus on management of postoperative pain to prevention of chronic pain in at-risk individuals.

PERSPECTIVE

This pilot study compared the effects of a 1-day preventive behavioral intervention (ACT) to TAU in at-risk veterans undergoing orthopedic surgery. Three months following the intervention, veterans receiving ACT exhibited quicker cessation of pain and opioid use. Focusing on preoperative pain management may help prevent chronic postsurgical pain.

摘要

目的:本初步研究旨在评估为期一天的接受与承诺疗法(ACT)工作坊在预防骨科手术后慢性疼痛和阿片类药物使用方面对“高危”退伍军人的疗效。

方法:在一项随机对照试验中,将 88 名接受骨科手术的高危退伍军人随机分为常规治疗(TAU;n=44)或 TAU 加为期一天的 ACT 工作坊(n=44)。在手术后 3 个月内评估疼痛水平和阿片类药物的使用情况。在基线和 3 个月随访时评估疼痛接受度和基于价值观的行为。完成 ACT 工作坊的参与者比接受 TAU 的参与者更快地达到疼痛和阿片类药物的停药。术后并发症对这些结果表现出调节作用,即 ACT 的效果在无并发症的患者中更大。疼痛接受度和基于价值观的行为的增加,是 ACT 中针对的过程,与更好的结果相关。这些有希望的结果值得在更大的临床试验中进一步研究。

结果:在高危退伍军人中,在手术前提供干预措施有可能将临床实践从关注术后疼痛管理转变为预防高危人群的慢性疼痛。

结论:高危退伍军人接受为期一天的预防性行为干预(ACT)与接受 TAU 相比,在接受骨科手术后更快地停止疼痛和阿片类药物的使用。术前关注疼痛管理可能有助于预防慢性术后疼痛。

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