Frade Porto Natalia, Delgado Fernández Juan, García Pallero María de Los Ángeles, Penanes Cuesta Juan Ramón, Pulido Rivas Paloma, Gil Simoes Ricardo
Servicio de Neurocirugía, Hospital Universitario de la Princesa, Madrid, España.
Servicio de Neurocirugía, Hospital Universitario de la Princesa, Madrid, España.
Neurocirugia (Engl Ed). 2019 May-Jun;30(3):149-154. doi: 10.1016/j.neucir.2018.03.005. Epub 2018 May 16.
Glioblastoma multiforme is the most common primary brain tumor, despite an aggressive clinical course, less than 2% of patients develop extraneural metastasis. We present a 72-year-old male diagnosed with a right temporal glioblastoma due to headache. He underwent total gross resection surgery and after that the patient was treated with adyuvant therapy. Five months after the patient returned with trigeminal neuralgia, and MRI showed an infratemporal cranial mass which infiltrates masticator space, the surrounding bone, the temporal muscle and superior cervical and parotid lymph nodes. The patient underwent a new surgery reaching partial resection of the temporal lesion. After that the patient continued suffering from disabling trigeminal neuralgia, that's why because of the bad clinical situation and the treatment failure we decided to restrict therapeutic efforts. The patient died 3 weeks after the diagnosis of extracranial metastasis.
多形性胶质母细胞瘤是最常见的原发性脑肿瘤，尽管临床病程凶险，但不到2%的患者会发生神经外转移。我们报告一例72岁男性，因头痛被诊断为右颞叶胶质母细胞瘤。他接受了全肿瘤切除术，术后接受辅助治疗。五个月后，患者因三叉神经痛复诊，MRI显示颞下颅骨肿块，侵犯咀嚼肌间隙、周围骨质、颞肌以及颈上和腮腺淋巴结。患者接受了再次手术，部分切除颞部病变。此后，患者仍持续遭受严重的三叉神经痛折磨，鉴于临床状况不佳且治疗失败，我们决定限制治疗措施。患者在被诊断为颅外转移3周后死亡。
