霉酚酸酯用于初治无肾脏受累的肉芽肿性多血管炎患者诱导缓解和维持缓解。
Mycophenolate mofetil for induction and maintenance of remission in naïve patients with granulomatosis with polyangiitis without renal involvement.
作者信息
Emad Yasser, Ragab Yasser, Rasker Johannes J
机构信息
Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Radiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
出版信息
Reumatol Clin (Engl Ed). 2020 Jul-Aug;16(4):294-297. doi: 10.1016/j.reuma.2018.03.007. Epub 2018 May 31.
Antineutrophil cytoplasmic antibodies (ANCA) associated vasculitides include granulomatosis with polyangiitis (GPA, previously called Wegener's), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA), previously called Churg-Strauss). In this report we used mycophenolate mofetil (MMF) and steroids to induce and maintain remission in two newly diagnosed cases with c-ANCA associated GPA. The two patients' maintained remission with no disease relapses during one year follow-up.
抗中性粒细胞胞浆抗体（ANCA）相关血管炎包括肉芽肿性多血管炎（GPA，以前称为韦格纳肉芽肿）、显微镜下多血管炎（MPA）和嗜酸性肉芽肿性多血管炎（EGPA，以前称为变应性肉芽肿性血管炎）。在本报告中，我们使用霉酚酸酯（MMF）和类固醇诱导并维持两名新诊断的与c-ANCA相关的GPA患者缓解。两名患者在一年的随访中维持缓解，无疾病复发。
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