Erbel R, Sievert H, Bussmann W D, Pop T, Bednarczyk I, Erdmann E, Meyer J
II. Med. Klinik und Poliklinik, Johannes-Gutenberg-Universität Mainz.
Z Kardiol. 1988 Dec;77(12):797-804.
An analysis of percutaneous transluminal angioplasty of the coarctation of the aorta in adults was evaluated in a cooperative study of the German Working Group of Angioplasty of the German Society of Cardiology. Dilation was performed in 18 patients with a mean age of 26 years (14-49 years). The success rate (gradient less than or equal to 20 mm Hg) was 78% regarding peak to peak gradient, 89% regarding mean gradient. The peak-to-peak gradient decreased from 82 +/- 16 mm Hg to 18 +/- 11 mm Hg. The diameter of the aortic isthmus increased from 0.7 +/- 0.3 cm to 1.3 +/- 0.4 cm (p less than 0.01). After six months only one restenosis occurred. The peak-to-peak gradient measured 10 +/- 12 mm Hg, the diameter 1.4 +/- 0.5 cm. In two patients a balloon rupture occurred without rupture-related complications. No patients died, no cross paralysis or aortic rupture occurred. In three of seven patients with trans-esophageal echocardiographic monitoring a small intimal flap was found; in one patient a media dissection occurred leading to a 15-min period of chest pain and spontaneous healing. In another patient successful dilation was controlled by acute control aortography and computer tomography. After discharge severe chest pain developed. A subtraction angiography of the aorta was negative. Six months later a biplane aortography of the distal thoracic aorta confirmed the diagnosis of aortic dissection type III DeBakey, previously diagnosed by transesophageal echocardiography.(ABSTRACT TRUNCATED AT 250 WORDS)
德国心脏病学会血管成形术工作组的一项合作研究对成人主动脉缩窄的经皮腔内血管成形术进行了分析。对18例平均年龄26岁(14 - 49岁)的患者进行了扩张术。峰峰值梯度方面的成功率(梯度小于或等于20 mmHg)为78%,平均梯度方面为89%。峰峰值梯度从82±16 mmHg降至18±11 mmHg。主动脉峡部直径从0.7±0.3 cm增加到1.3±0.4 cm(p < 0.01)。六个月后仅发生一例再狭窄。测量的峰峰值梯度为10±12 mmHg,直径为1.4±0.5 cm。两名患者发生球囊破裂,但无破裂相关并发症。无患者死亡,未发生交叉性瘫痪或主动脉破裂。在七例经食管超声心动图监测的患者中,三例发现小的内膜瓣;一例发生中膜夹层,导致胸痛15分钟并自发愈合。另一例患者通过急性控制性主动脉造影和计算机断层扫描确认扩张成功。出院后出现严重胸痛。主动脉减影血管造影结果为阴性。六个月后,胸段降主动脉的双平面主动脉造影证实了经食管超声心动图先前诊断的III型DeBakey主动脉夹层(摘要截短于250字)