Department of Neurology, University Cinical Center Tuzla, Prof. dr. Ibre Pašića bb, 75000, Tuzla, Bosnia and Herzegovina.
Neurology Clinic, Clinical Center of Serbia and School of Medicine, University of Belgrade, Dr Subotića 6, 11000, Belgrade, Serbia.
Neurol Sci. 2018 Aug;39(8):1445-1451. doi: 10.1007/s10072-018-3447-6. Epub 2018 May 19.
The aim of this study is to determine impairments of certain cognitive functions in certain vascular cognitive syndromes and to identify predictors of dementia.
One-year prospective study included 275 patients, who were hospitalized at the Department of Neurology Tuzla and therefore fulfilled certain criteria. Patients were divided into following subgroups of vascular cognitive impairment (VCI): dementia of strategic infarct (DSI), cortical dementia (CD), sub cortical dementia (SCD), hemorrhagic dementia (HD), and patients without dementia. Each of the patients underwent the clinical examination and scoring with appropriate measurement scales.
Some of the types of VCI were verified in 190 (69%) patients, and the most common was SCD (58%). There was statistically significant connection between the level of intelligence and occurrence of VCI in patients after stroke (p < 0.001). We found significant connection between occurrence of dementia and impairment in narrative memory, numerical memory, visual perceptive, and visual constructive functions in patients with dementia compared with non-demented (p = 0.0001). The executive functions were statistically impaired in patients with CD (p = 0.004) and SCD (p < 0.001). Patients without dementia have significantly better quality of life than the demented ones (p < 0.0001). The algorithm "tree of decision" can help us in the prediction of dementia based on the impairment of certain cognitive functions.
Vascular cognitive syndromes are common after stroke. Some of the cognitive functions are significantly impaired in patients with dementia. Impairment of the certain cognitive functions can help in predicting the onset of dementia. Patients without dementia have better quality of life.
本研究旨在确定某些血管性认知综合征中某些认知功能的障碍，并确定痴呆的预测因素。
这项为期 1 年的前瞻性研究纳入了 275 名在图兹拉神经科住院的患者，他们符合某些标准。患者被分为以下血管性认知障碍（VCI）亚组：战略梗死性痴呆（DSI）、皮质性痴呆（CD）、皮质下痴呆（SCD）、出血性痴呆（HD）和非痴呆患者。每位患者均接受了临床检查和适当测量量表的评分。
190 名（69%）患者被证实存在某些类型的 VCI，最常见的是 SCD（58%）。脑卒中后患者的智力水平与 VCI 的发生有统计学显著关联（p<0.001）。我们发现，与非痴呆患者相比，痴呆患者的叙事记忆、数字记忆、视觉感知和视觉建构功能受损与痴呆的发生有显著关联（p=0.0001）。CD 患者（p=0.004）和 SCD 患者（p<0.001）的执行功能有统计学上的损伤。非痴呆患者的生活质量明显优于痴呆患者（p<0.0001）。基于某些认知功能的损伤，决策树算法可以帮助我们预测痴呆的发生。
脑卒中后常发生血管性认知综合征。痴呆患者的某些认知功能明显受损。某些认知功能的损伤有助于预测痴呆的发生。非痴呆患者的生活质量更好。
