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[非洲爪蟾蝌蚪变态发育过程中各组织中皮质酮和醛固酮浓度的变化]

[Changes in corticosterone and aldosterone concentrations in various tissues of Xenopus laevis tadpoles during the metamorphosis].

作者信息

Leloup-Hatey J, Baloche S, Jolivet-Jaudet G

机构信息

Laboratoire de Physiologie générale et comparée du Muséum National d'Histoire Naturelle, Unité d'Endocrinologie comparée, associée au CNRS, Paris.

出版信息

C R Seances Soc Biol Fil. 1988;182(4):354-60.

PMID:2977958
Abstract

During the metamorphosis of Xenopus laevis tadpoles, tissue concentrations of corticosterone and aldosterone did not change significantly in forelegs and hindlegs; they increased in tail, liver, skin and intestine. The rise of corticosteroid concentrations appeared in tissues which were deeply transformed during the first part of the climax, when plasma levels of corticosteroids also increased. Highest tissue levels, attained at the mid-climax, were maintained at least until the end of metamorphosis although plasma concentrations of two steroids were then abruptly fallen. Tissues able to retain corticosteroids reacted as Vertebrate "target tissues" and transformations which took place in them could be dependent, at least partially, on corticosteroids.

摘要

在非洲爪蟾蝌蚪的变态过程中,前肢和后肢中皮质酮和醛固酮的组织浓度没有显著变化;它们在尾巴、肝脏、皮肤和肠道中增加。皮质类固醇浓度的升高出现在高潮期第一部分深度转变的组织中,此时血浆皮质类固醇水平也升高。在高潮中期达到的最高组织水平至少维持到变态结束,尽管此时两种类固醇的血浆浓度突然下降。能够保留皮质类固醇的组织表现为脊椎动物的“靶组织”,其中发生的转变可能至少部分依赖于皮质类固醇。

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