Department of Pharmacy, Loyola University Medical Center, United States.
Department of Emergency Medicine, Loyola University Medical Center, United States.
Am J Emerg Med. 2018 Aug;36(8):1528.e1-1528.e2. doi: 10.1016/j.ajem.2018.05.026. Epub 2018 May 18.
Fluoroquinolones, including levofloxacin, exhibit desirable antimicrobial characteristics, including broad spectrum of activity and excellent bioavailability. This widely prescribed class of antibiotics has come under scrutiny due to a new black box warning of adverse reactions. Central nervous system effects have been sparsely described in previous literature. We present a case of levofloxacin-induced psychosis in a patient without underlying psychological history.
氟喹诺酮类药物，包括左氧氟沙星，具有理想的抗菌特性，包括广谱活性和良好的生物利用度。由于新的不良反应黑框警告，这种广泛应用的抗生素类别受到了严格审查。以前的文献中很少描述中枢神经系统的影响。我们报告了一例无潜在心理病史的左氧氟沙星诱导的精神病病例。
