Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA.
Chem Commun (Camb). 2018 May 31;54(45):5768-5771. doi: 10.1039/c8cc03255f.
A high-throughput screening (HTS) method was devised to increase the rate of discovery and evaluation of nerve agent degradation catalysts. Using this HTS method, >90 solid state materials, predominantly metal-organic frameworks (MOFs), were analyzed for their ability to hydrolyze the nerve agent simulant methyl paraoxon at two pH values (8.0 and 10.0).
设计了一种高通量筛选 (HTS) 方法,以提高发现和评估神经毒剂降解催化剂的速度。使用这种 HTS 方法,分析了 >90 种固态材料,主要是金属有机骨架 (MOFs),以评估它们在两种 pH 值(8.0 和 10.0)下水解神经毒剂模拟物甲基对氧磷的能力。