Haeffs Tyler H, D'Amato Lindsay N, Khawaja Shehryar N, Keith David A, Scrivani Steven J
Dental Student, Harvard School of Dental Medicine, Boston, MA.
Orofacial Pain Medicine Consultant, Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore, Pakistan.
J Oral Maxillofac Surg. 2018 Oct;76(10):2081-2088. doi: 10.1016/j.joms.2018.04.018. Epub 2018 Apr 26.
Arthroscopic lysis and lavage surgery (AS) is an effective modality that can decrease pain and increase maximum interincisal opening (MIO) in patients with internal derangement (ID) of the temporomandibular joint (TMJ). However, some patients remain in pain or have limited mandibular range of motion despite AS. The purpose of this study was to determine the effectiveness, prevalence of adverse effects, and predictors of response to TMJ AS in patients with TMJ arthralgia and ID.
A retrospective cohort study was conducted using data of patients who had undergone AS by a single surgeon (D.A.K.) from September 2010 to April 2015 in the Department of Oral and Maxillofacial Surgery at Massachusetts General Hospital (Boston, MA). Variables, including demographic data, medical history, and clinical presentation, were extracted and analyzed. Criteria for surgical success were defined as a postoperative MIO of at least 35 mm and a postoperative pain level no higher than 3 on an 11-point Likert-type numeric verbal pain rating scale. Appropriate descriptive and analytic statistics were computed and significance was set at a P value less than .05.
Of the 247 participants, 226 (91.5%) were women. The mean age of the sample was 38 ± 15.4 years. Successful surgical outcome was achieved in 62.3% of patients. Based on logistic regression analysis, higher initial mean pain score and concurrent use of benzodiazepines were the only variables that predicted an unsuccessful surgical outcome (P < .001; P = .005). Adverse effects were reported by 13.4% of patients, the most common being postoperative increase in pain (13.4%), temporary malocclusion (1.2%), and temporary paresthesia in the preauricular region (0.4%).
The results from this study indicate that in patients with ID of the TMJ unresponsive to noninvasive treatments, high initial pain scores and concurrent use of benzodiazepines are correlated with an unsuccessful outcome after AS.
关节镜下粘连松解和灌洗手术(AS)是一种有效的治疗方式,可减轻颞下颌关节(TMJ)内紊乱(ID)患者的疼痛并增加最大切牙间开口度(MIO)。然而,部分患者在接受AS治疗后仍存在疼痛或下颌运动范围受限的情况。本研究旨在确定TMJ疼痛和ID患者接受TMJ AS治疗的有效性、不良反应发生率及治疗反应的预测因素。
采用2010年9月至2015年4月在马萨诸塞州综合医院(波士顿,马萨诸塞州)口腔颌面外科由同一位外科医生(D.A.K.)实施AS治疗的患者数据进行回顾性队列研究。提取并分析包括人口统计学数据、病史和临床表现等变量。手术成功的标准定义为术后MIO至少为35毫米,且在11点李克特型数字语言疼痛评分量表上术后疼痛程度不高于3分。计算适当的描述性和分析性统计数据,显著性设定为P值小于0.05。
247名参与者中,226名(91.5%)为女性。样本的平均年龄为38±15.4岁。62.3%的患者获得了成功的手术结果。基于逻辑回归分析,较高的初始平均疼痛评分和同时使用苯二氮䓬类药物是仅有的预测手术结果不成功的变量(P<0.001;P = 0.005)。13.4%的患者报告了不良反应,最常见的是术后疼痛加剧(13.4%)、暂时性错牙合(1.2%)和耳前区暂时性感觉异常(0.4%)。
本研究结果表明,对于TMJ ID且对非侵入性治疗无反应的患者,较高的初始疼痛评分和同时使用苯二氮䓬类药物与AS治疗后不成功的结果相关。