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An in-vitro model for tumor immunotherapy with antibody heteroconjugates.

作者信息

Jung G, Eberhard H J

出版信息

Immunol Today. 1988 Sep;9(9):257-60. doi: 10.1016/0167-5699(88)91304-7.

DOI:10.1016/0167-5699(88)91304-7
PMID:2978374
Abstract
摘要

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Characterization of a bispecific FLT3 X CD3 antibody in an improved, recombinant format for the treatment of leukemia.一种用于治疗白血病的改良重组形式双特异性FLT3 X CD3抗体的特性研究。
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Immunology. 1994 Jan;81(1):92-5.
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Gene transfer by retrovirus-derived shuttle vectors in the generation of murine bispecific monoclonal antibodies.逆转录病毒衍生穿梭载体介导的基因转移在小鼠双特异性单克隆抗体生成中的应用
Proc Natl Acad Sci U S A. 1990 Apr;87(8):2941-5. doi: 10.1073/pnas.87.8.2941.
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Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.单克隆抗体靶向超抗原：一类不同的抗肿瘤药物。
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J Clin Invest. 1992 Sep;90(3):1093-9. doi: 10.1172/JCI115925.
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Killing of human leukaemia/lymphoma B cells by activated cytotoxic T lymphocytes in the presence of a bispecific monoclonal antibody (alpha CD3/alpha CD19).在双特异性单克隆抗体（αCD3/αCD19）存在的情况下，活化的细胞毒性T淋巴细胞对人白血病/淋巴瘤B细胞的杀伤作用。
Clin Exp Immunol. 1992 Dec;90(3):368-75. doi: 10.1111/j.1365-2249.1992.tb05853.x.