Feng Wenxian, Li Li, Xu Xuchang, Liu Jidong, Yang Yang, Jiao Yunqi
Department of Neurosurgery, Central Hospital of Zhumadian, Zhumadian Henan, 463000, P.R.China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016 Nov 8;30(11):1404-1407. doi: 10.7507/1002-1892.20160289.
To evaluate the effectiveness of the posterior atlantoaxial lateral mass screw fixation and suboccipital decompression in the treatment of Arnold-Chiari malformation associated with atlantoaxial joint dislocation.
Between September 2012 and November 2015, 17 cases of Arnold-Chiari malformation associated with atlantoaxial dislocation were treated by the posterior atlantoaxial lateral mass screw fixation and suboccipital decompression and expansion to repair the dura mater and bone graft fusion. There were 10 males and 7 females, aged 35-65 years (mean, 51.4 years). The disease duration was 14 months to 15 years with an average of 7.4 years. According to Arnold-Chiari malformation classification, 13 cases were rated as type I, 3 cases as type II, and 1 case as type III-IV. Cervical nerve root stimulation and compression symptoms were observed in 12 cases, occipital foramen syndrome in 11 cases, cerebellar compression symptoms in 6 cases, and syringomyelia in 10 cases.
Primary healing of incision was obtained in the other patients except 1 patient who had postoperative cerebrospinal fluid leakage after removal of drainage tube at 3 days after operation, which was cured after 7 days. All patients were followed up 6 months to 2 years, with an average of 18.4 months. The neurological dysfunction was improved in different degrees after operation. The Japanese Orthopedic Association (JOA) score was significantly increased to 16.12±1.11 at 6 months from preoperative 11.76±2.01 (=13.596, =0.000); compression of spinal cord and medulla was improved. X-ray examination showed bone graft fusion at 6 months after operation. In 10 patients with spinal cord cavity, MRI showed empty disappearance in 3 cases, empty cavity lessening in 6 cases, and no obvious change in 1 case at 6 months.
Atlantoaxial lateral mass screw fixation and suboccipital decompression and expansion to repair the dura mater can obtain good effectiveness in the treatment of Arnold Chiari malformation associated with atlantoaxial transarticular dislocation.
评估寰枢椎后路侧块螺钉固定联合枕下减压术治疗合并寰枢关节脱位的Arnold-Chiari畸形的疗效。
2012年9月至2015年11月,对17例合并寰枢椎脱位的Arnold-Chiari畸形患者行寰枢椎后路侧块螺钉固定联合枕下减压、硬脑膜修补扩大及植骨融合术。其中男10例,女7例,年龄35~65岁,平均51.4岁。病程14个月至15年,平均7.4年。根据Arnold-Chiari畸形分型,Ⅰ型13例,Ⅱ型3例,Ⅲ~Ⅳ型1例。出现颈神经根刺激及受压症状12例,枕大孔综合征11例,小脑受压症状6例,脊髓空洞症10例。
除1例术后3天拔除引流管后出现脑脊液漏,经7天治愈外,其余患者切口均一期愈合。所有患者随访6个月至2年,平均18.4个月。术后神经功能障碍均有不同程度改善。日本骨科学会(JOA)评分由术前的11.76±2.01显著提高至术后6个月的16.12±1.11(t=13.596,P=0.000);脊髓及延髓受压情况改善。X线检查显示术后6个月植骨融合。10例合并脊髓空洞症患者,术后6个月MRI显示空洞消失3例,空洞缩小6例,1例无明显变化。
寰枢椎后路侧块螺钉固定联合枕下减压、硬脑膜修补扩大术治疗合并寰枢关节脱位的Arnold-Chiari畸形可取得良好疗效。