Center for Cerebrovascular Research, Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94110, USA.
Int J Mol Sci. 2018 May 22;19(5):1533. doi: 10.3390/ijms19051533.
Stroke is one of the most devastating complications of bone fracture, occurring in up to 4% of patients after surgical repair for hip fracture. Bone fracture and ischemic stroke have many common risk factors. The impact of bone fracture on stroke recovery has not drawn much attention in the research field. Bone fracture could occur in stroke patients at different times during the recovery phase, which steepens the trajectory of cognitive decline, greatly affects the quality of life, and causes a heavy burden on healthcare resources. In this paper, we reviewed the growing information on the pathophysiological mechanisms by which bone fracture may affect ischemic stroke recovery process.
中风是骨折最严重的并发症之一,在接受髋关节骨折手术后,多达 4%的患者会出现这种并发症。骨折和缺血性中风有许多共同的危险因素。骨折对中风恢复的影响在研究领域并没有引起太多关注。中风患者在恢复阶段的不同时间可能会发生骨折,这会使认知能力下降的轨迹更加陡峭,极大地影响生活质量,并给医疗资源带来沉重负担。本文综述了越来越多的信息,这些信息涉及骨折可能影响缺血性中风恢复过程的病理生理机制。