• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

克林霉素治疗的链球菌中毒性休克综合征患者使用多特异性静脉免疫球蛋白:系统评价和荟萃分析。

Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.

机构信息

London School of Hygiene and Tropical Medicine, United Kingdom.

Imperial College London, United Kingdom.

出版信息

Clin Infect Dis. 2018 Oct 15;67(9):1434-1436. doi: 10.1093/cid/ciy401.

DOI:10.1093/cid/ciy401
PMID:29788397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6186853/
Abstract

We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.

摘要

我们使用荟萃分析评估了静脉注射免疫球蛋白(IVIG)对克林霉素治疗的链球菌中毒性休克综合征患者死亡率的影响。与 IVIG 相关联,在单个随机对照研究和四个非随机对照研究中,死亡率从 33.7%显著下降至 15.7%,一致性良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0d6/6186853/f571a2176182/ciy40101.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0d6/6186853/f571a2176182/ciy40101.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0d6/6186853/f571a2176182/ciy40101.jpg

相似文献

1
Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.克林霉素治疗的链球菌中毒性休克综合征患者使用多特异性静脉免疫球蛋白:系统评价和荟萃分析。
Clin Infect Dis. 2018 Oct 15;67(9):1434-1436. doi: 10.1093/cid/ciy401.
2
Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study.多价静脉用免疫球蛋白治疗链球菌中毒性休克综合征患者的临床疗效:一项比较观察性研究。
Clin Infect Dis. 2014 Sep 15;59(6):851-7. doi: 10.1093/cid/ciu449. Epub 2014 Jun 13.
3
Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections.克林霉素和静脉注射免疫球蛋白的疗效及接触者发病风险在侵袭性 A 组链球菌感染中的作用。
Clin Infect Dis. 2014 Aug 1;59(3):358-65. doi: 10.1093/cid/ciu304. Epub 2014 Apr 29.
4
Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation.用于实验性链球菌中毒性休克的人静脉注射免疫球蛋白:细菌清除与炎症调节
J Antimicrob Chemother. 2006 Jul;58(1):117-24. doi: 10.1093/jac/dkl173. Epub 2006 May 2.
5
Puerperal widespread pyomyositis after group A streptococcal toxic shock syndrome.A组链球菌中毒性休克综合征后的产后广泛脓性肌炎
Isr Med Assoc J. 2008 Jun;10(6):483-4.
6
Infections due to group A streptococcus: new concepts and potential treatment strategies.A组链球菌感染:新概念与潜在治疗策略
Ann Acad Med Singap. 1997 Sep;26(5):691-3.
7
Prognostic factors for streptococcal toxic shock syndrome: systematic review and meta-analysis.链球菌中毒性休克综合征的预后因素:系统评价和荟萃分析。
BMJ Open. 2022 Dec 1;12(12):e063023. doi: 10.1136/bmjopen-2022-063023.
8
Severe group A streptococcal toxic shock syndrome presenting as primary peritonitis: a case report and brief review of the literature.严重 A 组链球菌中毒性休克综合征表现为原发性腹膜炎:病例报告及文献复习。
Int J Infect Dis. 2010 Sep;14 Suppl 3:e208-12. doi: 10.1016/j.ijid.2009.07.014. Epub 2009 Nov 13.
9
[Toxic shock-like syndrome caused by streptococci].[链球菌引起的中毒性休克样综合征]
Ned Tijdschr Geneeskd. 1999 Jul 10;143(28):1452-5.
10
Treatment of Necrotizing Soft Tissue Infections: IVIG.治疗坏死性软组织感染:IVIG。
Adv Exp Med Biol. 2020;1294:105-125. doi: 10.1007/978-3-030-57616-5_8.

引用本文的文献

1
A unique case of IUD associated group A Streptococci pyogenic ascites.一例罕见的宫内节育器相关A组链球菌化脓性腹水病例。
IDCases. 2025 Aug 18;41:e02348. doi: 10.1016/j.idcr.2025.e02348. eCollection 2025.
2
Managing toxic shock syndrome in immunosuppressed patient after liver transplantation from trauma to triumph: A case report.肝移植后免疫抑制患者中毒性休克综合征的管理:从创伤到成功的病例报告。
World J Clin Cases. 2025 Aug 26;13(24):106827. doi: 10.12998/wjcc.v13.i24.106827.
3
The impact of intravenous immunoglobulin therapy on resource utilization associated with viral respiratory tract infections.

本文引用的文献

1
Impact of Intravenous Immunoglobulin on Survival in Necrotizing Fasciitis With Vasopressor-Dependent Shock: A Propensity Score-Matched Analysis From 130 US Hospitals.静脉注射免疫球蛋白对伴有血管升压药依赖型休克的坏死性筋膜炎患者生存率的影响:来自美国130家医院的倾向评分匹配分析
Clin Infect Dis. 2017 Apr 1;64(7):877-885. doi: 10.1093/cid/ciw871.
2
Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study.多价静脉用免疫球蛋白治疗链球菌中毒性休克综合征患者的临床疗效:一项比较观察性研究。
Clin Infect Dis. 2014 Sep 15;59(6):851-7. doi: 10.1093/cid/ciu449. Epub 2014 Jun 13.
3
静脉注射免疫球蛋白疗法对与病毒性呼吸道感染相关的资源利用的影响。
Front Immunol. 2025 Aug 6;16:1513712. doi: 10.3389/fimmu.2025.1513712. eCollection 2025.
4
Optimizing Antibiotic Choice, Administration, and Duration in NSTI Treatment.优化坏死性软组织感染治疗中的抗生素选择、给药方式及疗程
Bioengineering (Basel). 2025 Jun 24;12(7):691. doi: 10.3390/bioengineering12070691.
5
Severe Pneumonia Due to Streptococcal Toxic Shock Syndrome in a Patient Positive for Influenza Virus Antigen: A Case Report.流感病毒抗原阳性患者的链球菌中毒性休克综合征所致重症肺炎:一例报告
Cureus. 2025 May 6;17(5):e83620. doi: 10.7759/cureus.83620. eCollection 2025 May.
6
Pediatric Necrotizing Fasciitis.小儿坏死性筋膜炎
J Pediatr Soc North Am. 2024 Feb 5;5(4):728. doi: 10.55275/JPOSNA-2023-728. eCollection 2023 Nov.
7
Immunomodulation in Pediatric Sepsis: A Narrative Review.儿童脓毒症中的免疫调节:一篇叙述性综述
J Clin Med. 2025 Apr 25;14(9):2983. doi: 10.3390/jcm14092983.
8
Quantifying Potential Immortal Time Bias in Observational Studies in Acute Severe Infection.量化急性重症感染观察性研究中潜在的不朽时间偏倚。
Open Forum Infect Dis. 2025 Mar 18;12(4):ofaf173. doi: 10.1093/ofid/ofaf173. eCollection 2025 Apr.
9
CD121b-positive neutrophils predict immunosuppression in septic shock.CD121b阳性中性粒细胞可预测脓毒性休克中的免疫抑制。
Front Immunol. 2025 Mar 31;16:1565797. doi: 10.3389/fimmu.2025.1565797. eCollection 2025.
10
Additional biomarkers and emm types associated with group A streptococcal toxic shock syndrome: a Japanese nationwide observational study.与A组链球菌中毒性休克综合征相关的其他生物标志物和emm类型:一项日本全国性观察性研究。
Eur J Clin Microbiol Infect Dis. 2025 Jun;44(6):1471-1480. doi: 10.1007/s10096-025-05116-6. Epub 2025 Apr 7.
Toxic shock syndrome surveillance in UK children.
英国儿童中毒性休克综合征监测。
Arch Dis Child. 2014 Dec;99(12):1078-82. doi: 10.1136/archdischild-2013-304741. Epub 2014 May 1.
4
Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections.克林霉素和静脉注射免疫球蛋白的疗效及接触者发病风险在侵袭性 A 组链球菌感染中的作用。
Clin Infect Dis. 2014 Aug 1;59(3):358-65. doi: 10.1093/cid/ciu304. Epub 2014 Apr 29.
5
Intravenous immunoglobulin in children with streptococcal toxic shock syndrome.静脉注射免疫球蛋白用于治疗患有链球菌中毒性休克综合征的儿童。
Clin Infect Dis. 2009 Nov 1;49(9):1369-76. doi: 10.1086/606048.
6
Predictors of death after severe Streptococcus pyogenes infection.严重化脓性链球菌感染后死亡的预测因素。
Emerg Infect Dis. 2009 Aug;15(8):1304-7. doi: 10.3201/eid1508.090264.
7
Morbidity and mortality of patients with invasive group A streptococcal infections admitted to the ICU.入住重症监护病房的侵袭性A组链球菌感染患者的发病率和死亡率。
Chest. 2006 Dec;130(6):1679-86. doi: 10.1378/chest.130.6.1679.
8
Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation.用于实验性链球菌中毒性休克的人静脉注射免疫球蛋白:细菌清除与炎症调节
J Antimicrob Chemother. 2006 Jul;58(1):117-24. doi: 10.1093/jac/dkl173. Epub 2006 May 2.
9
Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial.静脉注射免疫球蛋白G治疗链球菌中毒性休克综合征:一项欧洲随机、双盲、安慰剂对照试验。
Clin Infect Dis. 2003 Aug 1;37(3):333-40. doi: 10.1086/376630. Epub 2003 Jul 17.
10
Intravenous immunoglobulin therapy for streptococcal toxic shock syndrome--a comparative observational study. The Canadian Streptococcal Study Group.静脉注射免疫球蛋白治疗链球菌中毒性休克综合征——一项比较性观察研究。加拿大链球菌研究小组。
Clin Infect Dis. 1999 Apr;28(4):800-7. doi: 10.1086/515199.