克林霉素治疗的链球菌中毒性休克综合征患者使用多特异性静脉免疫球蛋白：系统评价和荟萃分析。
Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.
机构信息
London School of Hygiene and Tropical Medicine, United Kingdom.
Imperial College London, United Kingdom.
出版信息
Clin Infect Dis. 2018 Oct 15;67(9):1434-1436. doi: 10.1093/cid/ciy401.
Abstract
We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.
摘要
我们使用荟萃分析评估了静脉注射免疫球蛋白（IVIG）对克林霉素治疗的链球菌中毒性休克综合征患者死亡率的影响。与 IVIG 相关联，在单个随机对照研究和四个非随机对照研究中，死亡率从 33.7%显著下降至 15.7%，一致性良好。
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