Ben Jeddou K, Ben M'Barka F, Boukhris I, Arfaoui H, Baccar H, Khalfalah N, Ouhachi Z
Service de pharmacie, hôpital Charles-Nicolle, boulevard 9 Avril, 1006 Bab Saadoun, Tunis, Tunisie; Université de Monastir, faculté de pharmacie, Tunis, Tunisie.
Service de médecine interne, CHU Charles-Nicolle, Tunis, Tunisie; Université Tunis El Manar, faculté de médecine de Tunis, Tunis, Tunisie.
Rev Med Interne. 2018 Jul;39(7):546-550. doi: 10.1016/j.revmed.2017.11.013. Epub 2018 May 19.
Adverse events related to vitamin K antagonists (VKA) represent a major public health problem. Informative tools and educative program contributes to the reduction of iatrogenic risk. The purpose of our study is to assess representations and information needs of patients under VKA therapy in order to develop a suitable therapeutic education program.
Individual semi-structured interviews were conducted among both long term VKA therapy patient and patients initiating VKA. The thematic analysis allowed us to explore patient's speech qualitatively and semi-quantitatively.
The main needs in information concerned the modalities of treatment (27.6%), side effects (24.1%), precautions and management of VKA treatment (24.1%). Origin of the disease (P=0.022) and drug mechanism of action (0.012) were specially asked about by patients initiating their treatment.
Patients under VKA therapy reported needs for information on both their pathology and their anticoagulant therapy. The therapeutic education approach will enable us to adapt the educational tools and messages to the needs of patients under VKA therapy.
与维生素K拮抗剂（VKA）相关的不良事件是一个重大的公共卫生问题。信息工具和教育项目有助于降低医源性风险。我们研究的目的是评估接受VKA治疗的患者的认知和信息需求，以便制定合适的治疗教育项目。
对长期接受VKA治疗的患者和开始接受VKA治疗的患者进行了个体半结构化访谈。主题分析使我们能够对患者的言语进行定性和半定量探索。
主要的信息需求涉及治疗方式（27.6%）、副作用（24.1%）、VKA治疗的注意事项和管理（24.1%）。开始治疗的患者特别询问了疾病的起源（P=0.022）和药物作用机制（0.012）。
接受VKA治疗的患者报告了对其病情和抗凝治疗信息的需求。治疗教育方法将使我们能够根据接受VKA治疗的患者的需求调整教育工具和信息。
