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光生物调节疗法在口腔黏膜炎管理中的应用：寻找最佳临床治疗参数。

Photobiomodulation therapy in the management of oral mucositis: search for the optimal clinical treatment parameters.

机构信息

Division of Oral Medicine, Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA.

Oral Biology and Biomedical Engineering, University at Buffalo, Buffalo, NY, USA.

出版信息

Support Care Cancer. 2018 Oct;26(10):3319-3321. doi: 10.1007/s00520-018-4262-6. Epub 2018 May 22.

DOI:10.1007/s00520-018-4262-6
PMID:29789949
Abstract

This commentary attempts to clarify the setting of photobiomodulation (BPM) therapy in the management of oral mucositis. The suggested dose range balances efficacy data with our current understanding about PBM safety. The literature about the molecular basis of photobiomodulation and its controversial relationship to malignant transformation is briefly presented.

摘要

本述评旨在阐明光生物调节（BPM）疗法在口腔黏膜炎治疗中的应用背景。建议的剂量范围兼顾了疗效数据和我们目前对 PBM 安全性的认识。文中简要介绍了光生物调节的分子基础及其与恶性转化的争议性关系的相关文献。

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本文引用的文献

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Long-term survival of a randomized phase III trial of head and neck cancer patients receiving concurrent chemoradiation therapy with or without low-level laser therapy (LLLT) to prevent oral mucositis.头颈部癌症患者在接受同期放化疗时是否联合低水平激光治疗（LLLT）预防口腔黏膜炎的随机 III 期临床试验的长期生存结果。
Oral Oncol. 2017 Aug;71:11-15. doi: 10.1016/j.oraloncology.2017.05.018. Epub 2017 Jun 3.
2
Craniofacial Wound Healing with Photobiomodulation Therapy: New Insights and Current Challenges.光生物调节疗法促进颅面部伤口愈合：新见解与当前挑战
J Dent Res. 2016 Aug;95(9):977-84. doi: 10.1177/0022034516648939. Epub 2016 May 9.
3
光生物调节在预防和治疗口腔黏膜炎中的临床应用：MASCC/ISOO 成员的真实经验。
Support Care Cancer. 2023 Jul 21;31(8):481. doi: 10.1007/s00520-023-07919-9.
4
Photobiomodulation Therapy in the Prevention and Treatment of Radiodermatitis in Breast Cancer Patients: Systematic Review.光生物调节疗法在乳腺癌患者放射性皮炎防治中的应用：系统评价
J Lasers Med Sci. 2022 Oct 2;13:e42. doi: 10.34172/jlms.2022.42. eCollection 2022.
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Does Photobiomodulation Affects CK10 and CK14 in Oral Mucositis Radioinduced Repair?光生物调节是否影响放射性口腔黏膜炎修复过程中的 CK10 和 CK14？
Int J Mol Sci. 2022 Dec 9;23(24):15611. doi: 10.3390/ijms232415611.
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