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实体器官移植受者感染的皮肤表现

Cutaneous Manifestations of Infections in Solid Organ Transplant Recipients.

作者信息

Pettit Cory J, Mazurek Katherine, Kaffenberger Benjamin

机构信息

College of Medicine, The Ohio State University, 370 W 9th Ave, Columbus, OH, 43201, USA.

University of Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA.

出版信息

Curr Infect Dis Rep. 2018 May 22;20(7):16. doi: 10.1007/s11908-018-0621-1.

Abstract

PURPOSE OF REVIEW

Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in the immunocompromised. Quality research in this field is lacking, and this articles seeks to review the literature and present a guide to physicians in order for them to suspect certain infections by their cutaneous presentation.

RECENT FINDINGS

The cutaneous presentation of opportunistic infections in transplant patients is extremely varied. However, as more case reports are published, certain patterns specific to individual organisms are emerging. In addition, early recognition is improving outcomes and systemic antibiotic therapy success. Early and correct recognition of disseminated infection in the immunocompromised host can be aided by close attention to cutaneous findings. This allows early and correct antibiotic therapy and improves outcomes.

摘要

综述目的

移植后感染因其表现多样,给医生带来了巨大挑战。这些感染许多是在皮肤受损后通过接种开始,或经血行播散至皮肤,使得感染的皮肤表现成为免疫功能低下患者的重要诊断线索。该领域缺乏高质量研究,本文旨在回顾文献并为医生提供指南,以便他们根据皮肤表现怀疑某些感染。

最新发现

移植患者机会性感染的皮肤表现极为多样。然而,随着更多病例报告的发表,特定病原体的某些模式正在显现。此外,早期识别正在改善治疗结果并提高全身抗生素治疗的成功率。密切关注皮肤表现有助于早期正确识别免疫功能低下宿主的播散性感染。这能实现早期正确的抗生素治疗并改善治疗结果。

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