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酒精性心肌病大鼠的心房去极化

Atria Depolarization in Rats with Alcoholic Cardiomyopathy.

作者信息

Smirnova S L, Roshchevskaya I M, Roshchevsky M P, Tsorin I B, Stolyaruk V N, Vititnova M B, Kolik L G, Kryzhanovskii S A

机构信息

Komi Research Center, Ural Branch, Russian Academy of Sciences, Syktyvkar, Russia.

Zakusov Research Institute of Pharmacology, Moscow, Russia.

出版信息

Dokl Biol Sci. 2018 Mar;479(1):41-43. doi: 10.1134/S0012496618020035. Epub 2018 May 22.

Abstract

Chronotopography of atrial subepicardium depolarization has been studied in a rat model of alcoholic cardiomyopathy. Formation of independent sources of initial atrial activity has been detected in the right and left atria. These sources induced the formation of several depolarization fronts that propagated autonomously, and this can be regarded as the cause of atrial arrhythmia.

摘要

在酒精性心肌病大鼠模型中研究了心房心外膜下 depolarization 的时间拓扑学。在右心房和左心房中检测到了初始心房活动的独立来源的形成。这些来源诱导了几个自主传播的 depolarization 前沿的形成,这可被视为房性心律失常的原因。 (注:原文中“depolarization”未翻译,因为不清楚具体所指的医学专业术语准确中文表述,一般可译为“去极化”等,这里保留英文以便准确传达原文信息)

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