Einstein Institute for Heart and Vascular Health, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
J Card Fail. 2011 Oct;17(10):844-9. doi: 10.1016/j.cardfail.2011.05.008. Epub 2011 Jun 16.
Alcohol abuse can cause cardiomyopathy indistinguishable from other types of dilated nonischemic cardiomyopathy. Most heavy drinkers remain asymptomatic in the earlier stages of disease progression, and many never develop the familiar clinical manifestations that typify heart failure. We review the current thinking on the pathophysiology, clinical characteristics, and treatments available for alcoholic cardiomyopathy. The relationship of alcohol to heart disease is complicated by the fact that in moderation, alcohol has been shown to afford a certain degree of protection against cardiovascular disease.
酗酒可导致心肌病,其与其他类型扩张型非缺血性心肌病无法区分。大多数重度饮酒者在疾病进展的早期阶段无症状,且许多人从未出现心力衰竭的典型临床表现。我们综述了目前对酒精性心肌病的病理生理学、临床特征和治疗方法的认识。由于适度饮酒已被证明可在一定程度上预防心血管疾病,因此酒精与心脏病之间的关系较为复杂。