单克隆抗体的位点特异性修饰。使用裸鼠异种移植系统对铟-111标记抗体的研究。 - Suppr

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超能文献

Site-specific modification of monoclonal antibodies. Studies of 111indium-labeled antibodies using nude mouse xenograft systems.

作者信息

Alvarez V L, Lopes A D, Lee C, Coughlin D J, Rodwell J D, McKearn T J

机构信息

CYTOGEN Corporation, Princeton, New Jersey.

出版信息

Targeted Diagn Ther. 1988;1:283-315.

PMID:2979060

Abstract

摘要

相似文献

Site-specific modification of monoclonal antibodies. Studies of 111indium-labeled antibodies using nude mouse xenograft systems.单克隆抗体的位点特异性修饰。使用裸鼠异种移植系统对铟-111标记抗体的研究。

Targeted Diagn Ther. 1988;1:283-315.

Radioiodinated monoclonal antibodies in the imaging and treatment of human renal cell carcinoma xenografts in nude mice.放射性碘化单克隆抗体在裸鼠人肾细胞癌异种移植瘤的成像与治疗中的应用。

Targeted Diagn Ther. 1988;1:245-82.

111Indium-capromab pendetide unexpectedly localizes to renal cell carcinoma.铟-喷曲肽意外地定位于肾细胞癌。

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Monoclonal antibodies in human renal cell carcinoma and their use in radioimmune localization and therapy of tumor xenografts.

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Immunolocalisation of an anti-EMA monoclonal antibody to a renal carcinoma xenograft.抗上皮膜抗原（EMA）单克隆抗体在肾癌异种移植瘤中的免疫定位

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[Study of radioimmunodetection with In-111 labeled monoclonal anti-colorectal carcinoma antibody (19-9, 17-1A) F (ab')2 fragments].

Kaku Igaku. 1987 Jul;24(7):919-25.

[Imaging and biodistribution of 111In-labeled anti-carcinoembryonic antigen monoclonal antibodies in nude mice bearing human colon cancer xenografts].

Zhonghua Zhong Liu Za Zhi. 1989 Jul;11(4):254-6.

Radioimmunodetection of human cervical carcinoma xenograft by 111In-labeled monoclonal antibody MAb Cx-99.用¹¹¹铟标记的单克隆抗体MAb Cx - 99对人宫颈癌异种移植瘤进行放射免疫检测。

Int J Gynaecol Obstet. 1995 Jul;49 Suppl:S33-8. doi: 10.1016/0020-7292(95)02407-4.

Dosimetry and pharmacokinetics of monoclonal antibody A6H with human renal cell carcinoma xenografts: single dose study.单克隆抗体A6H在人肾细胞癌异种移植模型中的剂量学与药代动力学：单剂量研究

Int J Rad Appl Instrum B. 1991;18(5):527-37. doi: 10.1016/0883-2897(91)90114-z.

Dual isotope study of iodine-125 and indium-111-labeled antibody in athymic mice.无胸腺小鼠中碘-125和铟-111标记抗体的双同位素研究。

J Nucl Med. 1989 Mar;30(3):374-84.

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Site-specific conjugation of HIV-1 tat peptides to IgG: a potential route to construct radioimmunoconjugates for targeting intracellular and nuclear epitopes in cancer.HIV-1反式激活因子（tat）肽与IgG的位点特异性偶联：构建用于靶向癌症细胞内和细胞核表位的放射免疫偶联物的潜在途径。

Eur J Nucl Med Mol Imaging. 2006 Mar;33(3):301-10. doi: 10.1007/s00259-005-1908-7. Epub 2005 Oct 29.

Modification of monoclonal antibody carbohydrates by oxidation, conjugation, or deoxymannojirimycin does not interfere with antibody effector functions.通过氧化、偶联或脱氧甘露基野尻霉素对单克隆抗体碳水化合物进行修饰不会干扰抗体的效应器功能。

Cancer Immunol Immunother. 1994 Jan;38(1):23-30. doi: 10.1007/BF01517166.

Carbohydrate-derivatized immunoconjugate of the anti-(carcinoembryonic antigen) monoclonal antibody C46: immunohistological reactivity and pharmacokinetic comparison with a randomly derivatized C46 immunoconjugate.抗癌胚抗原单克隆抗体C46的碳水化合物衍生化免疫缀合物：与随机衍生化的C46免疫缀合物的免疫组织学反应性和药代动力学比较

Cancer Immunol Immunother. 1990;32(4):207-13. doi: 10.1007/BF01741702.

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