Department of Periodontology and Oral Implantology, Faculty of Medicine and Health Sciences, School of Dental Medicine, Ghent University, Ghent, Belgium.
Private Practice Periodontology and Oral Implantology, Geluwe, Belgium.
Clin Implant Dent Relat Res. 2018 Aug;20(4):515-521. doi: 10.1111/cid.12612. Epub 2018 May 23.
The purpose of this study is to evaluate the 10-year outcome of 25 patients with immediate loading in the edentulous mandible.
Twenty-five patients were consecutively treated with 5 immediately loaded fluoride-modified implants in the edentulous mandible. Implant survival and bone loss were evaluated by an external researcher comparing digital periapical radiographs taken during recall visits with baseline (at implant insertion). Statistical descriptive analysis and nonparametric tests were performed using SPSS v23, multilevel analysis was performed by means of R version 3.1.0. to identify risk factors for bone loss.
Twenty-one patients (8 males, 13 females, mean age 68.4, range 49-84) responded to the 10-year recall invitation. No implants were lost during follow-up, resulting in a 100% survival rate. After 10 years, bleeding on probing and plaque were present at 49.5% and 67.6% of the sites, respectively. The mean pocket probing depth was 3.77 mm (SD 0.73, range 3.0-6.83). Bone loss on implant level after 3, 12, 24, and 120 months was 0.16 mm (SD 0.33, range 0-1.75), 0.14 mm (SD 0.24, range 0-1.05), 0.17 mm (SD 0.27, range 0-1.5), and 0.49 mm (SD 1.08, range 0-7.8). Five implants were identified with or at risk for progressive bone loss. Forty-seven percent of the implants did not show any bone loss after 10 years in function and 87% lost less than 1 mm. Multilevel statistical analysis identified 2-year bone loss as a predictor for bone loss after 10 years of function.
Immediate loading of 5 fluoride-modified dental implants with a fixed prosthetic rehabilitation is a predictable and reliable treatment in the edentulous mandible, based on a 100% implant survival and limited peri-implant bone loss. Implants used for immediate loading in the edentulous mandible who are showing early bone loss may be at higher risk to develop peri-implantitis.
本研究旨在评估 25 例即刻负载在下颌无牙颌患者中的 10 年疗效。
连续对 25 例下颌无牙颌患者使用 5 个即刻负载的氟化物改性种植体进行治疗。通过外部研究人员比较在复诊时拍摄的数字化根尖片与基线（植入时），评估种植体存活率和骨吸收情况。使用 SPSS v23 进行统计描述性分析和非参数检验，使用 R 版本 3.1.0 进行多水平分析，以确定骨吸收的危险因素。
21 名患者（8 名男性，13 名女性，平均年龄 68.4 岁，范围 49-84 岁）对 10 年召回邀请做出了回应。随访期间无种植体丢失，存活率为 100%。10 年后，探诊出血和菌斑分别在 49.5%和 67.6%的位点存在。平均探诊牙周袋深度为 3.77mm（SD 0.73，范围 3.0-6.83）。植入物水平的骨吸收在 3、12、24 和 120 个月后分别为 0.16mm（SD 0.33，范围 0-1.75）、0.14mm（SD 0.24，范围 0-1.05）、0.17mm（SD 0.27，范围 0-1.5）和 0.49mm（SD 1.08，范围 0-7.8）。有 5 个种植体被认为存在或有进展性骨吸收的风险。47%的种植体在功能上 10 年后没有任何骨吸收，87%的种植体骨吸收小于 1mm。多水平统计分析表明，2 年的骨吸收是功能 10 年后骨吸收的预测因素。
在下颌无牙颌中使用 5 个氟化物改性牙种植体进行即刻负载固定修复是一种可预测和可靠的治疗方法，具有 100%的种植体存活率和有限的种植体周围骨吸收。在下颌无牙颌中即刻负载的种植体，如果早期出现骨吸收，可能有更高的发展为种植体周围炎的风险。
