Department of Chemistry, Fudan University, 2005 Songhu Road, Shanghai, 200438, P. R. China.
School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, 411201, P. R. China.
Chem Asian J. 2018 Sep 4;13(17):2543-2548. doi: 10.1002/asia.201800591. Epub 2018 Jul 12.
A sulfonylation of benzylic C-H bonds of aryl(o-tolyl)methanones with arylsulfonyl hydrazides or arylsulfonyl chlorides has been developed. Arylsulfonyl hydrazides and arylsulfonyl chlorides were employed as sulfonylating reagents respectively to complete this transformation. During the reaction, enols were generated in situ from aryl(o-tolyl)methanones under UV irradiation, and subsequently reacted with sulfonyl radicals to provide a range of aryl(2-(arylsulfonylmethyl)aryl)methanones.
芳基（邻甲苯基）甲酮的苄位 C-H 键与芳基磺酰基肼或芳基磺酰氯发生磺酰化反应。分别使用芳基磺酰基肼和芳基磺酰氯作为磺酰化试剂来完成这种转化。在反应过程中，芳基（邻甲苯基）甲酮在紫外光照射下原位生成烯醇，然后与磺酰基自由基反应，生成一系列芳基（2-（芳基磺酰基甲基）芳基）甲酮。
