Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund, Sweden.
Osteoarthritis Cartilage. 2018 Aug;26(8):1008-1016. doi: 10.1016/j.joca.2018.05.004. Epub 2018 May 22.
Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older (>40 years) patients with preoperative mechanical symptoms (MS) improved more in patient-reported outcomes after meniscal surgery than those without MS.
Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up. Questionnaires included self-reported presence of MS (i.e., sensation of catching and/or locking) and the Knee injury and Osteoarthritis Outcome Score (KOOS). We analyzed between-group differences in change in KOOS from baseline to 52 weeks, using an adjusted mixed linear model.
150 younger patients (mean age 31 (SD 7), 67% men) and 491 older patients (mean age 54 (SD 9), 53% men) constituted the baseline cohorts. Patients with MS generally had worse self-reported outcomes before surgery. At 52 weeks follow-up, younger patients with preoperative MS had improved more in KOOS scores than younger patients without preoperative MS (adjusted mean difference 10.5, 95% CI: 4.3, 16.6), but did not exceed the absolute postoperative KOOS scores observed for those without MS. No difference in improvement was observed between older patients with or without MS (adjusted mean difference 0.7, 95% CI: -2.6, 3.9).
Younger patients (≤40 years) with preoperative MS experienced greater improvements after arthroscopic surgery compared to younger patients without MS. Our observational study result needs to be confirmed in randomized trials.
患有退行性或外伤性半月板撕裂的患者患膝关节骨关节炎的风险很高。我们研究了术前有机械症状(MS)的年轻(≤40 岁)和年长(>40 岁)患者在半月板手术后的患者报告结局改善情况是否优于无 MS 的患者。
来自丹麦南部膝关节镜队列研究(KACS)的接受关节镜手术治疗半月板撕裂的患者在手术前、术后 12 周和 52 周时完成在线问卷调查。问卷包括自我报告的 MS 存在情况(即感觉捕捉和/或锁定)和膝关节损伤和骨关节炎结果评分(KOOS)。我们使用调整后的混合线性模型分析了从基线到 52 周时 KOOS 变化的组间差异。
150 名年轻患者(平均年龄 31(SD 7),67%为男性)和 491 名年长患者(平均年龄 54(SD 9),53%为男性)构成了基线队列。有 MS 的患者术前自我报告结局通常较差。在 52 周随访时,术前有 MS 的年轻患者在 KOOS 评分方面的改善程度大于术前无 MS 的年轻患者(调整后的平均差异 10.5,95%CI:4.3,16.6),但未超过无 MS 患者的术后绝对 KOOS 评分。在有或没有 MS 的年长患者之间,改善程度没有差异(调整后的平均差异 0.7,95%CI:-2.6,3.9)。
与无 MS 的年轻患者(≤40 岁)相比,术前有 MS 的年轻患者(≤40 岁)在关节镜手术后经历了更大的改善。我们的观察性研究结果需要在随机试验中得到证实。