HIV 暴露婴儿的脊柱结核：两例可能为先天性传播的病例。

Spinal Tuberculosis in Young HIV-exposed Infants: Two Cases of Probable Congenital Transmission.

机构信息

From the Department of Pediatrics, Hospital Central de Maputo, Maputo, Moçambique.

Department of Pediatrics, University of California Los Angeles School of Medicine, Los Angeles, California.

出版信息

Pediatr Infect Dis J. 2019 Mar;38(3):e48-e50. doi: 10.1097/INF.0000000000002118.

DOI:10.1097/INF.0000000000002118

PMID:29794650

Abstract

The presentation of congenital tuberculosis (TB) is varied, with frequent extrapulmonary disease, but congenital spinal TB has been rarely reported. We present 2 cases of spinal TB (1 confirmed, 1 clinical diagnosis) in HIV-exposed infants with likely congenital transmission. Increased vigilance for congenital TB, including uncommon presentations, is needed, particularly in countries with high HIV and TB prevalence.

摘要

先天性结核病（TB）的表现多种多样，常伴有肺外疾病，但先天性脊柱 TB 则很少见。我们报告了 2 例 HIV 暴露婴儿的脊柱 TB（1 例确诊，1 例临床诊断），可能为先天性传播所致。需要提高对先天性 TB 的警惕性，包括不常见的表现，尤其是在 HIV 和 TB 高发的国家。