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腓骨近端截骨术治疗内侧间室膝关节骨关节炎:短期预后的术前因素。

Proximal fibular osteotomy to treat medial compartment knee osteoarthritis: Preoperational factors for short-term prognosis.

机构信息

Department of Orthopaedic Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China.

Key laboratory of biomechanics of Hebei Province, Shijiazhuang, Hebei, P.R. China.

出版信息

PLoS One. 2018 May 24;13(5):e0197980. doi: 10.1371/journal.pone.0197980. eCollection 2018.

DOI:10.1371/journal.pone.0197980
PMID:29795669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5967722/
Abstract

OBJECTIVE

The purpose of this study was to determine the association between preoperational factors and patients' short-term outcome after proximal fibular osteotomy (PFO) and to provide a basis for detailed surgical indication and patient selection.

METHODS

This was a retrospective study of patients undergoing PFO between January 2015 and December 2015. Preoperational clinical data including gender, age, duration of disease, visual analogue score (VAS) and American Knee Society (KSS) score were collected. The radiological factors including hip-knee-ankle angle (HKA angle), condyle-plateau angle (CP angle), Kellgren and Lawrence grade (KL grade), joint space width of both compartments and settlement value were also considered. Patients were followed for at 12 months postoperatively. Both clinical and functional KSS scores were obtained. The outcome of interest was divided into clinical outcome and functional outcome. For each, two criteria were defined: satisfaction and significant improvement. Satisfaction is characterized by a KSS clinical or functional score over 70 points (excellent and good results); significant improvement refers to an increase in KSS scores of more than 15 points. Bivariate logistic regression for the association between preoperational factors and outcomes of interest was performed. Multivariable logistic regression analyses were used to detect the independent factors affecting the outcomes.

RESULTS

A total of 84 patients and 111 knees were followed-up. Of these, 17 knees were from males and 94 were from females. The average age was 59.45±8.82 years. The average preoperational VAS score, KSS clinical and functional score were 7.08±1.41 points, 49.14±10.95 points and 44.97±17.71 points, respectively. According to KL grading, there were 17 knees of grade 2, 47 knees of grade 3, and 47 knees of grade 4. In clinical outcomes, there were 51 knees in the satisfaction group and 77 knees in the significant improvement group. In functional outcomes, 43 knees were in the satisfaction group and 76 knees in the significant improvement group. KSS clinical score (OR = 1.134, 95%CI = 1.067-1.205, P = 0.000) was the independent factor associated with clinical satisfaction. Age (OR = 1.072, 95%CI = 1.000-1.150, P = 0.048), VAS score (OR = 1.679, 95%CI = 1.041-2.706, P = 0.033), KSS clinical (OR = 1.072, 95%CI = 1.005-1.144, P = 0.034) and functional (OR = 1.100, 95%CI = 1.044-1.159, P = 0.000) score, HKA angle (OR = 1.345, 95%CI = 1.119-1.617, P = 0.002) and settlement value (OR = 7.540, 95%CI = 1.307-43.484, P = 0.024) were the independent factors associated with functional satisfaction. KSS clinical (OR = 0.905, 95%CI = 0.850-0.963, P = 0.002) score, CP angle (OR = 0.760, 95%CI = 0.593-0.973, P = 0.030) and medial joint space width (OR = 0.001, 95%CI = 0.000-0.107, P = 0.003) were the independent factors associated with significant clinical improvement; VAS score (OR = 1.582, 95%CI = 1.042-2.402, P = 0.031), KSS functional (OR = 0.888, 95%CI = 0.838-0.942, P = 0.000) score, HKA angle (OR = 1.292, 95%CI = 1.101-1.518, P = 0.002) and settlement value (OR = 9.990, 95%CI = 1.485-67.197, P = 0.018) were the independent factors associated with significant functional improvement.

CONCLUSIONS

The independent factors affecting postoperative clinical outcome after PFO were KSS clinical score, CP angle and medial joint space width. In addition, the independent factors that influenced functional outcome included age, VAS score, KSS score, HKA angle and settlement value. As objective radiological evidence, HKA angle and settlement value could be used as an important basis for patient selection for PFO.

摘要

目的

本研究旨在确定术前因素与腓骨近端截骨术(PFO)后患者短期预后的关系,为详细的手术适应证和患者选择提供依据。

方法

这是一项回顾性研究,纳入 2015 年 1 月至 2015 年 12 月期间接受 PFO 治疗的患者。收集了包括性别、年龄、病程、视觉模拟评分(VAS)和美国膝关节协会(KSS)评分在内的术前临床数据。还考虑了包括髋膝踝角(HKA 角)、髁间窝角(CP 角)、Kellgren 和 Lawrence 分级(KL 分级)、内外侧关节间隙宽度和沉降值在内的影像学因素。患者术后随访 12 个月。获得了临床和功能 KSS 评分。感兴趣的结果分为临床结果和功能结果。对于每个结果,定义了两个标准:满意度和显著改善。满意度是指 KSS 临床或功能评分超过 70 分(优秀和良好结果);显著改善是指 KSS 评分增加超过 15 分。对术前因素与感兴趣结果之间的关系进行了二元逻辑回归分析。采用多变量逻辑回归分析检测影响结果的独立因素。

结果

共 84 例患者和 111 膝接受了随访。其中,17 膝为男性,94 膝为女性。平均年龄为 59.45±8.82 岁。平均术前 VAS 评分、KSS 临床和功能评分分别为 7.08±1.41 分、49.14±10.95 分和 44.97±17.71 分。根据 KL 分级,有 17 膝为 2 级,47 膝为 3 级,47 膝为 4 级。在临床结果中,51 膝为满意组,77 膝为显著改善组。在功能结果中,43 膝为满意组,76 膝为显著改善组。KSS 临床评分(OR=1.134,95%CI=1.067-1.205,P=0.000)是与临床满意度相关的独立因素。年龄(OR=1.072,95%CI=1.000-1.150,P=0.048)、VAS 评分(OR=1.679,95%CI=1.041-2.706,P=0.033)、KSS 临床(OR=1.072,95%CI=1.005-1.144,P=0.034)和功能(OR=1.100,95%CI=1.044-1.159,P=0.000)评分、HKA 角(OR=1.345,95%CI=1.119-1.617,P=0.002)和沉降值(OR=7.540,95%CI=1.307-43.484,P=0.024)是与功能满意度相关的独立因素。KSS 临床评分(OR=0.905,95%CI=0.850-0.963,P=0.002)、CP 角(OR=0.760,95%CI=0.593-0.973,P=0.030)和内侧关节间隙宽度(OR=0.001,95%CI=0.000-0.107,P=0.003)是与显著临床改善相关的独立因素;VAS 评分(OR=1.582,95%CI=1.042-2.402,P=0.031)、KSS 功能评分(OR=0.888,95%CI=0.838-0.942,P=0.000)、HKA 角(OR=1.292,95%CI=1.101-1.518,P=0.002)和沉降值(OR=9.990,95%CI=1.485-67.197,P=0.018)是与显著功能改善相关的独立因素。

结论

影响 PFO 术后临床结果的独立因素是 KSS 临床评分、CP 角和内侧关节间隙宽度。此外,影响功能结果的独立因素包括年龄、VAS 评分、KSS 评分、HKA 角和沉降值。HKA 角和沉降值作为客观影像学证据,可作为 PFO 患者选择的重要依据。

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