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攀登阿空加瓜山期间的睡眠呼吸障碍。

Sleep respiratory disturbances during the ascent to Mount Aconcagua.

作者信息

Ortiz-Naretto Alvaro Emilio, Pereiro Miriam Patricia, Ernst Glenda, Borsini Eduardo Enrique

机构信息

Hospital Francisco Muñiz, Medicine Respiratory Unit - Buenos Aires City - Buenos Aires - Argentina.

Asociación Andina de Medicina para la Altura, Curso Medicina para la Altura - Mendoza City - Mendoza - Argentina.

出版信息

Sleep Sci. 2018 Jan-Feb;11(1):20-24. doi: 10.5935/1984-0063.20180005.

Abstract

INTRODUCTION

Mountaineers exposed to hypobaric hypoxia (HH) show high-altitude periodic breathing (PB).

OBJECTIVE

To analyze high-altitude PB during the ascent of Mount Aconcagua (Argentina).

MATERIALS AND METHODS

Descriptive study in healthy volunteers using respiratory polygraphy (RP) at different altitudes.

RESULTS

We studied 8 andinist, mean age: 36 years old (25-51), body mass index (BMI) of 23.6 (20.9-28.7) and 22.77 (20.9-27.7) upon return, <0.01. RP without PB showed a lower Oxygen Desaturation Index (ODI) and a lower Apnea-Hypopnea-Index (AHI); 5.43 (0 - 20) versus 45.95 (2-122) <0.001 and 3.9 (0-15.5) versus 44.35 (4-115) <0.001. AHI increased with altitude at the expense of central apneas and hypopneas: <0.05.

CONCLUSION

High-altitude PB is frequent above 2,581m.a.s.l. And it is characterized by short cycles. None of the mountaineers showed PB at baseline; however, high-altitude PB occurred in all subjects above 4,900 m.a.s.l.

摘要

引言

暴露于低压缺氧环境的登山者会出现高原周期性呼吸(PB)。

目的

分析攀登阿空加瓜山(阿根廷)过程中的高原PB。

材料与方法

对健康志愿者进行描述性研究,在不同海拔高度使用呼吸多导仪(RP)。

结果

我们研究了8名登山者,平均年龄:36岁(25 - 51岁),返回时体重指数(BMI)为23.6(20.9 - 28.7)和22.77(20.9 - 27.7),P<0.01。无PB的RP显示较低的氧去饱和指数(ODI)和较低的呼吸暂停低通气指数(AHI);分别为5.43(0 - 20)对45.95(2 - 122),P<0.001以及3.9(0 - 15.5)对44.35(4 - 115),P<0.001。AHI随海拔升高而增加,以中枢性呼吸暂停和低通气为代价:P<0.05。

结论

海拔高于2581米时高原PB很常见,且周期较短。所有登山者在基线时均未出现PB;然而,海拔高于4900米时所有受试者均出现了高原PB。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e755/5916571/e82fcef8b4b9/ssci-11-01-0020-g01.jpg

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