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与单纯疱疹病毒2型感染相关的妊娠相关性噬血细胞性淋巴组织细胞增生症:诊断难题

Pregnancy-related Hemophagocytic Lymphohistiocytosis Associated with Herpes Simplex Virus-2 Infection: A Diagnostic Dilemma.

作者信息

Nasser M Farhan, Sharma Shorabh, Albers Elizabeth, Sharma Sapna, Duggal Anurag

机构信息

Internal Medicine, Cleveland Clinic Akron General.

Internal Medicine, SBH Health System.

出版信息

Cureus. 2018 Mar 20;10(3):e2352. doi: 10.7759/cureus.2352.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory disorder characterized by the uncontrolled proliferation of lymphocytes and histiocytes with hemophagocytic activity in the bone marrow. To our knowledge, there have been a few reported cases of pregnancy-related HLH. This case highlights the importance of considering HLH in a pregnant woman along with other diagnoses, such as HELLP (which stands for hemolysis, elevated liver enzyme levels, and low platelet levels) syndrome and hemolytic anemias. It points to the challenges of diagnosing and managing pregnancy-related HLH due to a similarity in presentation with other conditions.

摘要

噬血细胞性淋巴组织细胞增生症(HLH)是一种严重的炎症性疾病,其特征是淋巴细胞和组织细胞在骨髓中不受控制地增殖,并具有噬血细胞活性。据我们所知,妊娠相关HLH的报道病例较少。本病例强调了在孕妇中考虑HLH以及其他诊断的重要性,如HELLP(代表溶血、肝酶水平升高和血小板水平降低)综合征和溶血性贫血。它指出了由于与其他病症表现相似,诊断和管理妊娠相关HLH的挑战。

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