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综述:炎症性肠病中的肠道除菌

Review: gut sterilization in inflammatory bowel disease.

作者信息

Hodgson H J

机构信息

Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

出版信息

Aliment Pharmacol Ther. 1987 Oct;1(5):359-65. doi: 10.1111/j.1365-2036.1987.tb00635.x.

DOI:10.1111/j.1365-2036.1987.tb00635.x
PMID:2979679
Abstract

Achieving a substantial reduction in the bacterial flora of the gut is a theoretically attractive means of treating inflammatory bowel disease, particularly colonic disease. There are practical difficulties in obtaining a sustained reduction of the colonic bacterial count, and the potential role of such a treatment regimen is therefore the initiation of remission. The data in the literature supporting such a suggestion are anecdotal, and a controlled study is indicated.

摘要

大幅减少肠道细菌群落从理论上来说是治疗炎症性肠病,尤其是结肠疾病的一种颇具吸引力的方法。要持续降低结肠细菌数量存在实际困难,因此这种治疗方案的潜在作用是引发病情缓解。文献中支持这一观点的数据多为轶事性的,所以需要进行对照研究。

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