Lykov A P, Bondarenko N A, Poveshchenko O V, Kabakov A V, Surovtseva M A, Kim I I, Kazakov O V, Poveshchenko A F
Research Institute of Clinical and Experimental Lymphology -Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Bull Exp Biol Med. 2018 May;165(1):121-126. doi: 10.1007/s10517-018-4112-z. Epub 2018 May 24.
We studied the effect of intramuscular injections of bone marrow mesenchymal stromal cells on microcirculation parameters in an ischemic limb of Wistar rats. It was shown that transplantation of mesenchymal stem cells with or without erythropoietin stimulates angiogenesis in the ischemic zone. An essential role in angiogenesis stimulation is played by cytokines and growth factors.
我们研究了肌肉注射骨髓间充质基质细胞对Wistar大鼠缺血肢体微循环参数的影响。结果表明,无论有无促红细胞生成素,间充质干细胞的移植均可刺激缺血区血管生成。细胞因子和生长因子在刺激血管生成中起重要作用。