Levy S, Moszkowicz D, Poghosyan T, Beauchet A, Chandeze M -M, Vychnevskaia K, Peschaud F, Bouillot J -L
AP-HP, Department of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, 9 Av Charles de Gaulle, 92104, Boulogne-Billancourt Cedex, France.
Versailles St-Quentin-en-Yvelines/Paris Saclay University, UFR des sciences de la santé Simone Veil, 78180, Montigny-Le-Bretonneux, France.
Hernia. 2018 Oct;22(5):773-779. doi: 10.1007/s10029-018-1785-1. Epub 2018 May 23.
Treatment of chronic mesh infections (CMI) after parietal repair is difficult and not standardized. Our objective was to present the results of a standardized surgical treatment including maximal infected mesh removal.
Patients who were referred to our center for chronic mesh infection were analyzed according to CMI risk factors, initial hernia prosthetic cure, CMI characteristics and treatments they received to achieve a cure.
Thirty-four patients (mean age 54 ± 13 years; range 23-72), were included. Initial prosthetic cure consisted of 26 incisional hernias and eight groin or umbilical hernias of which 21% were considered potentially contaminated because of three intestinal injuries, two stomas and two strangulated hernias. The mesh was synthetic in all cases. CMI appeared after a mean of 83 days (range 30-6740) and was characterized by chronic leaking in 52 cases (50%), an abscess in 22 cases (21%) and synchronous hernia recurrence in 17 cases (16.5%). Eighty-six reinterventions were necessary, including 36 mesh removals (42%), and 13 intestinal resections for entero-cutaneous fistula (15%). The CMI persistence rate was 81% (35 reinterventions out of 43) when mesh removal was voluntarily limited to infected and/or not incorporated material, but was 44% when mesh removal was voluntarily complete (19 reinterventions out of 43; p < 0.001). On average, 3.4 interventions (1-11) were necessary to achieve a cure, after 2.8 years (0-6). Fourteen incisional hernia recurrences occurred (41%).
Treatment of chronic mesh infection is lengthy and resource-intensive, with a high risk of hernia recurrence. Maximal mesh removal is mandatory.
腹壁修补术后慢性补片感染(CMI)的治疗困难且不规范。我们的目的是展示包括最大程度切除感染补片在内的标准化手术治疗的结果。
根据CMI危险因素、初始疝修补假体治愈情况、CMI特征以及为实现治愈所接受的治疗,对转诊至我们中心治疗慢性补片感染的患者进行分析。
纳入34例患者(平均年龄54±13岁;范围23 - 72岁)。初始假体治愈包括26例切口疝和8例腹股沟疝或脐疝,其中21%因3例肠损伤、2例造口和2例绞窄性疝被认为有潜在污染。所有病例的补片均为合成材料。CMI平均在83天(范围30 - 6740天)后出现,其特征为52例(50%)慢性渗漏、22例(21%)脓肿和17例(16.5%)同步疝复发。需要进行86次再次干预,包括36次补片切除(42%)和13次因肠皮肤瘘进行的肠切除(15%)。当补片切除自愿限于感染和/或未融合材料时,CMI持续率为81%(43次中有35次再次干预),但当补片切除自愿完全时,持续率为44%(43次中有19次再次干预;p < 0.001)。平均需要3.4次干预(1 - 11次)才能实现治愈,时间为2.8年(0 - 6年)。发生了14例切口疝复发(41%)。
慢性补片感染的治疗耗时且资源密集,疝复发风险高。必须最大程度切除补片。