Instituto de Ciencias Marinas de Andalucía (CSIC), Puerto Real, Cádiz, Spain.
Clin Transl Oncol. 2018 Dec;20(12):1612-1616. doi: 10.1007/s12094-018-1897-1. Epub 2018 May 23.
Madrid's CNIO (Spanish National Oncological Research Center) ranks among the three first institutions in the world, specifically dedicated to cancer research. CNIO research mainly focuses on three aspects: use of stem cells to fix problematic cancer damage, searches for genes that cause cancer disease, and use of drug design to manage oncological disorders.
The main goal of this study is to determine the effectiveness of the 'translation' of basic discoveries generated at this cancer research center, into new interventions aimed at preventing and treating various types of cancer, with bibliometric criteria.
A corpus of published articles and citations received by CNIO between 1998 and 2016 has been retrieved from the Web of Science (WoS) database. Bibliometric indicators considered here are: citation practices, use of journals on the basis of their impact factors, scientific literature citing CNIO publications, and international connectedness of CNIO researchers.
A total of 3510 articles were published by CNIO between 1998 and 2016, 23% of which in journals with impact factors between 10 and 15 and above 15. Along the same period, the institution received 135,769 citations published in more than 5800 journals, where the most important citing journals were the Plos One with 3.6% of all the citing articles, Oncotarget with 1.8%, and Scientific Reports with 1.2%. The highest number of citations was 18,005 in 2007; in terms of average citation rate, the first ranked CNIO research program was in the area of experimental therapeutics (77.79%), followed by molecular oncology (68.1%). This position was provided by the active growth in citation to the articles whose themes are related to the problems of the consequences of the design of preclinical drug candidates and the study of oncological disorders.
From this study on a number of bibliometric characteristics of the Spanish National Oncological Research Center (CNIO), we conclude that the publication activity (since 2006 its scientific production has increased in about 83%), the number of high-quality journals used per year, the high influence, and impact of the journals and organizations citing the institution, consolidate its image as a top-notch oncological research center.
马德里的西班牙国家肿瘤学研究中心（CNIO）是全球排名前三的癌症研究机构之一。CNIO 的研究主要集中在三个方面：利用干细胞修复癌症损伤、寻找致癌基因、以及设计药物来治疗肿瘤疾病。
本研究旨在利用文献计量学标准，确定该癌症研究中心的基础发现转化为新的干预措施，以预防和治疗各种类型癌症的效果。
从 Web of Science（WoS）数据库中检索了 1998 年至 2016 年期间 CNIO 发表的文章和引文。这里考虑的文献计量指标有：引文实践、根据影响因子使用期刊、引用 CNIO 出版物的科学文献、以及 CNIO 研究人员的国际联系。
1998 年至 2016 年间，CNIO 共发表了 3510 篇文章，其中 23%发表在影响因子在 10-15 之间和 15 以上的期刊上。同期，该机构共收到 135769 篇在 5800 多种期刊上发表的引文，其中最重要的引文期刊是 Plos One（3.6%的所有引文文章）、Oncotarget（1.8%）和 Scientific Reports（1.2%）。2007 年的引文数最高，为 18005 次；就平均引文率而言，排名第一的 CNIO 研究项目是实验治疗学（77.79%），其次是分子肿瘤学（68.1%）。这一排名是由于与临床前药物候选物设计的后果问题和肿瘤疾病研究相关主题的文章的引文活跃度增加而提供的。
从对西班牙国家肿瘤学研究中心（CNIO）的一些文献计量特征的研究中，我们得出结论，该中心的出版活动（自 2006 年以来，其科研产出增加了约 83%）、每年使用的高质量期刊数量、期刊和引用该机构的组织的高影响力和高影响力，巩固了其作为顶级肿瘤学研究中心的形象。
