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[冰连清咽喷雾剂治疗急慢性咽炎的多中心随机对照研究]

[A multicenter randomized controlled study on the treatment of acute and chronic pharyngitis with Binglianqingye Spray].

作者信息

Chen J J, Yin S K, Liu S X, Zhou H F, Zheng H L, Kong W J

机构信息

Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Sixth People's Hospital of Shanghai Jiao Tong University.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 5;32(1):1-6. doi: 10.13201/j.issn.1001-1781.2018.01.001.

Abstract

To further evaluate the clinical efficacy and safety of Binglianqingye Spray on acute and chronic pharyngitis by clinical observation. A randomized, double-blind and multicenter clinical trial which served Jinsangzi Tablet and Jinhoujian Spray as the control groups was conducted to observe the effect of Binglianqingye Spray on 360 patients with acute and chronic pharyngitis. Binglianqingye Spray could significantly improve the symptoms with the exact clinical efficacy of the acute pharyngitis or chronic pharyngitis, such as sore throat, pharyngeal mucosa and uvula, dry throat burning, headache, cough, pharynx posterior wall lymphoid follicles hyperemia swelling and mandibular angle lymph node swelling and so on, but it occasionally occurred urine abnormalities and urine sugar adverse reactions. At the same time, the taste satisfaction was 82.1%. The combined effects of Binglianqingye Spray on the treatment of acute pharyngitis or chronic pharyngitis are well, the adverse reaction is rare and the patient's compliance is high.

摘要

通过临床观察进一步评价冰连清咽喷雾剂治疗急、慢性咽炎的临床疗效及安全性。采用随机、双盲、多中心临床试验,以金嗓子含片和金喉健喷雾剂为对照组,观察冰连清咽喷雾剂治疗360例急、慢性咽炎患者的疗效。冰连清咽喷雾剂能显著改善急、慢性咽炎的症状,如咽痛、咽黏膜及悬雍垂、咽干灼热、头痛、咳嗽、咽后壁淋巴滤泡充血肿胀及下颌角淋巴结肿大等,但偶有尿常规异常及尿糖不良反应。同时,口感满意度为82.1%。冰连清咽喷雾剂治疗急、慢性咽炎疗效确切,不良反应少,患者依从性高。

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