Zhou T J, Zhang J C, Lu W, Zhao F, Li X F, Chen B
Department of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Department of Critical Care Medicine, Zhongshan Hospital, Fudan University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Dec 20;31(24):1880-1883. doi: 10.13201/j.issn.1001-1781.2017.24.004.
To investigate the predictive value of parathyroid hormone levels and decreases for postoperative hypocalcemia after total thyroidectomy. We reviewed 71 consecutive patients who underwent total thyroidectomy, measured postoperative hypocalcemia, parathyroid hormone (PTH) values within 24 hours after surgery, divided them into subgroups accroding to hypocalcemia symptom. Combining with postoperative serum calcium，postoperative PTH values and decreases (△PTH), we used the receiver operating characteristic curve (ROC) analysis to assessment of predictive value. The mean value of postoperative serum calcium, postoperative PTH and △PTH between subgroups have a significant difference (<0.01). ROC area under the curve (AUC) of △PTH is 0.9706, with cutoff value 0.7366. AUC of postoperative PTH is 0.9580, with cutoff value 14.82 ng/L. The postoperative PTH and △PTH is a reliable indicator to judging postoperative hypocalcemia after total thyroidectomy.
探讨甲状旁腺激素水平及其下降幅度对甲状腺全切除术后低钙血症的预测价值。我们回顾性分析了71例连续接受甲状腺全切除术的患者，测定术后低钙血症情况、术后24小时内甲状旁腺激素（PTH）值，并根据低钙血症症状将患者分为亚组。结合术后血清钙、术后PTH值及其下降幅度（△PTH），采用受试者工作特征曲线（ROC）分析评估其预测价值。各亚组间术后血清钙、术后PTH及△PTH的平均值差异有统计学意义（<0.01）。△PTH的曲线下面积（AUC）为0.9706，截断值为0.7366。术后PTH的AUC为0.9580，截断值为14.82 ng/L。术后PTH及△PTH是判断甲状腺全切除术后低钙血症的可靠指标。
