Hu C H, Wei H Z, He S, Liu X, Li Y C
Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, 100073, Beijing, China.
Department of Otorhinolaryngology, the First Hospital of Harbin.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Dec 5;31(23):1824-1827;1832. doi: 10.13201/j.issn.1001-1781.2017.23.011.
To investigate the imaging characteristics of bony erosion, fungal culture and related factors in allergic fungal rhinosinusitis (AFRS). Sixty cases of AFRS were reviewed in this study. The characteristics of Computed Tomography and Magnetic Resonance Imaging including positive rate of bony erosion, eroded sites, disease extension and sinus expansion were summarized. Fungal culture and identification of nasal secretion were done. The correlation between the degree of sinus expansion, species of fungi and bony erosion was evaluated by statistical analysis. Of the 60 patients, 18 (30%) had bony erosion. There was a significant difference in the proportion of bone erosion among the sinuses (<0.05). The most commonly eroded site was the ethmoid sinus. The orbit were the most common adjacent anatomic spaces to exhibit disease extension, and anterior cranial fossa is the second most common. Statistical analysis revealed a significant association(<0.05)of bone erosion with sinus expansion. The positive rate of fungal culture was 51.3%, among which the most common is Aspergillus. Statistical analysis shows no association(>0.05)of bone erosion with specific fungi. Bone erosion is an important imaging feature of AFRS. Bone erosion may cause by sinus expansion. Extension of disease into the orbit or intracranial cavity results from a natural progression of disease after erosion occurs. Specific fungal species that can cause bone erosion was found.
探讨变应性真菌性鼻窦炎（AFRS）骨质侵蚀的影像学特征、真菌培养及相关因素。本研究回顾了60例AFRS病例。总结了计算机断层扫描和磁共振成像的特征，包括骨质侵蚀的阳性率、侵蚀部位、疾病扩展及鼻窦扩张情况。进行了鼻分泌物的真菌培养和鉴定。通过统计分析评估鼻窦扩张程度、真菌种类与骨质侵蚀之间的相关性。60例患者中，18例（30%）有骨质侵蚀。各鼻窦间骨质侵蚀比例有显著差异（<0.05）。最常被侵蚀的部位是筛窦。眼眶是最常见出现疾病扩展的相邻解剖间隙，前颅窝是第二常见的。统计分析显示骨质侵蚀与鼻窦扩张有显著关联（<0.05）。真菌培养阳性率为51.3%，其中最常见的是曲霉菌。统计分析显示骨质侵蚀与特定真菌无关联（>0.05）。骨质侵蚀是AFRS的重要影像学特征。骨质侵蚀可能由鼻窦扩张引起。疾病扩展至眼眶或颅内腔是侵蚀发生后疾病自然进展的结果。发现了可导致骨质侵蚀的特定真菌种类。
