Wei X, Nian J B, Wang G, Zhang Y L, Cai S E, Liu S Z
Department of Otolaryngology Head and Neck Surgery，Hainan General Hospital，the Otolaryngology Head and Neck Surgery Hospital of Hainan，Haikou，570311，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Nov;30(22):1754-1757. doi: 10.13201/j.issn.1001-1781.2016.22.003.
To explore the clinic characters and the associated factors for the onset of the sinus fungus ball disease. Analyze 52 cases who have received surgery with sinus fungus ball disease retrospectively. The effect factors of age, sex, occupation, the side of the lesion, involving sinus group number, accompany with merger polyps or not, presence of nasal septum deviation, vesicular middle turbinate, paradoxical middle turbinate, infraorbital cells，routine blood leukocyte classification, serum specific IgE, pathogenic fungi species have all been taken into consideration for statistical analysis. In 52 cases of sinus fungus ball disease, 36 cases only suffered in maxillary sinus, 1 case only suffered in ethmoid sinus, 4 cases only suffered in sphenoid sinus, 7 cases suffered from two sinus lesions with the combination of maxillary sinus and ethmoid sinus in all, 4 cases fuffered from three sinus lesions with the combination of maxillary sinus, ethmoid sinus and sphenoid sinus in 2 cases, maxillary sinus, ethmoid sinus and frontal sinus in 2 cases. 26 cases have the lesion on left side,17 cases on the right side, 8 cases on both sides. Aspergillus is the main pathogenic fungus for sinus fungus ball. Maxillary sinus is the most susceptible single sinus for sinus fungus ball. Nasal polyps is commonly seen in multiple sinuses fungus ball(<0.01). Single sphenoid sinus fungus ball is more commonly seen in the patients with diabetes mellitus(<0.01). Lesion side of sinus fungus ball has nothing to do with the nasal anatomy abnormalities of nasal septum deviation, vesicular middle turbinate, paradoxical middle turbinate, infraorbital cells. The present study indicates that maxillary sinus fungus ball is the most common type for sinus fungus ball. Aspergillus is the main pathogenic fungus for sinus fungus ball. Nasal polyps is more involved in multiple sinuses fungus ball,Single sphenoid sinus fungus ball is more commonly seen in the patients with diabetes mellitus. Lesion side of sinus fungus ball has none relationship with common nasal anatomy abnormalities.
探讨鼻窦真菌球病的临床特点及发病相关因素。回顾性分析52例接受手术治疗的鼻窦真菌球病患者。对年龄、性别、职业、病变侧别、累及鼻窦组数、是否合并息肉、鼻中隔偏曲、泡状中鼻甲、反常中鼻甲、眶下气房、血常规白细胞分类、血清特异性IgE、致病真菌种类等影响因素进行统计分析。52例鼻窦真菌球病患者中，单纯上颌窦发病36例，单纯筛窦发病1例，单纯蝶窦发病4例，累及两个鼻窦病变共7例（其中上颌窦合并筛窦4例，上颌窦合并蝶窦2例，上颌窦合并额窦1例），累及三个鼻窦病变共4例（其中上颌窦、筛窦和蝶窦2例，上颌窦、筛窦和额窦2例）。左侧病变26例，右侧病变17例，双侧病变8例。曲霉菌是鼻窦真菌球的主要致病真菌。上颌窦是鼻窦真菌球最易受累的单个鼻窦。鼻息肉多见于多鼻窦真菌球（<0.01）。单纯蝶窦真菌球多见于糖尿病患者（<0.01）。鼻窦真菌球的病变侧别与鼻中隔偏曲、泡状中鼻甲、反常中鼻甲、眶下气房等鼻腔解剖异常无关。本研究表明，上颌窦真菌球是鼻窦真菌球最常见的类型。曲霉菌是鼻窦真菌球的主要致病真菌。鼻息肉在多鼻窦真菌球中更易累及，单纯蝶窦真菌球多见于糖尿病患者。鼻窦真菌球的病变侧别与常见鼻腔解剖异常无关。
