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[单侧与双侧经皮椎体后凸成形术治疗Kümmell病的疗效比较]

[Effectiveness comparison between unilateral and bilateral percutaneous kyphoplasty for Kümmell disease].

作者信息

Sun Yuliang, Xiong Xiaoming, Wan Dun, Deng Xuangeng, Shi Huagang, Song Simao, Wu Xiao, Zhou Jie, Yang Maoyi

机构信息

Department of Spine Surgery, Sichuan Province Orthopedics Hospital, Chengdu Sichuan, 610041, P.R.China.

Department of Spine Surgery, Sichuan Province Orthopedics Hospital, Chengdu Sichuan, 610041,

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017 Sep 15;31(9):1086-1091. doi: 10.7507/1002-1892.201704055.

Abstract

OBJECTIVE

To compare the effectiveness between unilateral and bilateral percutaneous kyphoplasty (PKP) in the treatment of Kümmell disease.

METHODS

The clinical data of 45 patients with Kümmell disease that met the criteria between January 2014 and February 2016 were analyzed retrospectively. Among them, 26 cases were treated by unilateral PKP (unilateral group), 19 cases were treated by bilateral PKP (bilateral group). There was no significant difference in gender, age, disease duration, injured vertebral segment, bone mineral density (T value), and the preoperative visual analogue scale (VAS) score, Oswestry disability index (ODI), anterior vertebral height, and kyphosis Cobb angle between 2 groups ( >0.05). The operation time, intraoperative fluoroscopy times, amount of injected bone cement, and hospitalization time were recorded, and the situation of bone cement leakage was observed. The VAS score, ODI, anterior vertebral height, and kyphosis Cobb angle were evaluated before operation, at 1 day after operation, and at last follow-up.

RESULTS

Bone cement leakage during the operation were found in 4 cases (15.38%) of unilateral group and 3 cases (15.79%) of bilateral group without obvious neurological symptoms; there was no significant difference in the incidence of bone cement leakage between 2 groups ( =0.000, =1.000). The operation time, intraoperative fluoroscopy times, and amount of injected bone cement in the unilateral group were significantly lower than those in the bilateral group ( <0.05); but there was no significant difference in the hospitalization time between 2 groups ( >0.05). The X-ray film examination showed that there was no pulmonary embolism in all patients at 1 day after operation. All the patients were followed up 12-24 months, with an average of 16.4 months. There was no complication such as vertebral re-fracture or cement block displacement in the injured vertebra. The VAS score, ODI, anterior vertebral height, and kyphosis Cobb angle at 1 day after operation and at last follow-up were significantly improved when compared with preoperative values in 2 groups ( <0.05); the VAS score and ODI in 2 groups were further reduced at last follow-up when compared with the value at 1 day after operation ( <0.05), but the anterior vertebral height and kyphosis Cobb angle in 2 groups at last follow-up did not change significantly ( >0.05). There was no significant difference in above indexes at 1 day after operation and at last follow-up between 2 groups ( >0.05).

CONCLUSION

Both unilateral and bilateral PKP can achieve good effectiveness in treatment of Kümmell disease. But the unilateral puncture technique possesses advantages such as shorter operation time, less radiation dose, and less amount of injected bone cement.

摘要

目的

比较单侧与双侧经皮椎体后凸成形术(PKP)治疗Kümmell病的疗效。

方法

回顾性分析2014年1月至2016年2月间45例符合标准的Kümmell病患者的临床资料。其中,26例行单侧PKP治疗(单侧组),19例行双侧PKP治疗(双侧组)。两组在性别、年龄、病程、受伤椎体节段、骨密度(T值)、术前视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、椎体前缘高度和后凸Cobb角方面差异均无统计学意义(P>0.05)。记录手术时间、术中透视次数、骨水泥注入量及住院时间,并观察骨水泥渗漏情况。分别于术前、术后1天及末次随访时评估VAS评分、ODI、椎体前缘高度和后凸Cobb角。

结果

单侧组有4例(15.38%)、双侧组有3例(15.79%)在手术中出现骨水泥渗漏,均无明显神经症状;两组骨水泥渗漏发生率差异无统计学意义(P=0.000,P=1.000)。单侧组的手术时间、术中透视次数及骨水泥注入量均显著低于双侧组(P<0.05);但两组住院时间差异无统计学意义(P>0.05)。术后1天X线片检查显示所有患者均无肺栓塞。所有患者均获随访12~24个月,平均16.4个月。伤椎均未出现椎体再骨折或骨水泥块移位等并发症。两组术后1天及末次随访时的VAS评分、ODI、椎体前缘高度和后凸Cobb角与术前相比均显著改善(P<0.05);两组末次随访时的VAS评分和ODI较术后1天进一步降低(P<0.05),但两组末次随访时的椎体前缘高度和后凸Cobb角变化不明显(P>0.05)。两组术后1天及末次随访时上述指标差异无统计学意义(P>0.05)。

结论

单侧与双侧PKP治疗Kümmell病均能取得良好疗效。但单侧穿刺技术具有手术时间短、辐射剂量少、骨水泥注入量少等优点。

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本文引用的文献

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Vertebroplasty: what is important and what is not.椎体成形术:重要的和不重要的。
AJNR Am J Neuroradiol. 2009 Nov;30(10):1835-9. doi: 10.3174/ajnr.A1732. Epub 2009 Aug 27.
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