Spampinato N, Stassano P, Cammarota A, Musumeci A, Mannacio V, Iorio D, Covino E
Department of Cardiac Surgery, 2nd Medical School, University of Naples, Italy.
J Card Surg. 1988 Sep;3(3 Suppl):383-90. doi: 10.1111/jocs.1988.3.3s.383.
From January 1976 through December 1986, seven different types of bioprostheses have been implanted in our center. The following bioprostheses (total 1,414) were implanted in 1,098 patients: Carpentier-Edwards 567, Hancock 302, Liotta 268, Ionescu-Shiley 127, Angell-Shiley 72, Vascor 68, Implamedic 10. Follow-up ranged from 1 to 12 years, cumulative duration of follow-up was 6,747 patient-years and 8,637 valve-years, being 95.4% complete. Cumulative actuarial probability of being free from tissue valve failure (TVF) was 85.1% +/- 2.0% at 10 years, and 61.6% +/- 9.6% at 12 years. Actuarial probability of being free from TVF was 71.2% +/- 10.8% at 12 years for Carpentier-Edwards, 51% +/- 21.7% at 12 years for Hancock, 73.4% +/- 14.1% at 11 years for Angell-Shiley, 53% +/- 27.4% at 9 years for Liotta, 68% +/- 14.8% at 11 years for Ionescu-Shiley, 53.2% +/- 22.2% at 7 years for Vascor, 72.2% +/- 21.5% at 5 years for Implamedic bioprostheses. In this comparison of seven different bioprostheses, there is a large group of valves behaving in a very similar way. Only a few prostheses showed a constant and early negative trend.
从1976年1月至1986年12月，我们中心共植入了7种不同类型的生物假体。以下生物假体（共1414个）被植入1098例患者体内：Carpentier-Edwards型567个、Hancock型302个、Liotta型268个、Ionescu-Shiley型127个、Angell-Shiley型72个、Vascor型68个、Implamedic型10个。随访时间为1至12年，累积随访时长为6747患者年和8637瓣膜年，完成率为95.4%。组织瓣膜失效（TVF）的累积精算概率在10年时为85.1%±2.0%，在12年时为61.6%±9.6%。Carpentier-Edwards型在12年时TVF的精算概率为71.2%±10.8%，Hancock型在12年时为51%±21.7%，Angell-Shiley型在11年时为73.4%±14.1%，Liotta型在9年时为53%±27.4%，Ionescu-Shiley型在11年时为68%±14.8%，Vascor型在7年时为53.2%±22.2%，Implamedic生物假体在5年时为72.2%±21.5%。在这7种不同生物假体的比较中，有一大组瓣膜的表现非常相似。只有少数假体呈现出持续且早期的负面趋势。
