G.W.W. School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, USA.
G.W.W. School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, USA; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, USA.
Hear Res. 2018 Aug;365:127-140. doi: 10.1016/j.heares.2018.05.011. Epub 2018 May 19.
In this work, a three-dimensional computational model of the gerbil ear is used to investigate the generation of the 2f-f and 2f-f distortion product otoacoustic emissions (DPOAEs). In order to predict both the distortion and reflection sources, cochlear roughness is modeled by introducing random inhomogeneities in the outer hair cell properties. The model was used to simulate the generation of DPOAEs in response to a two-tone stimulus for various primary stimulus levels and frequency ratios. As in published experiments, the 2f-f DPOAEs are mostly dominated by the distortion component while the 2f-f DPOAEs are dominated by the reflection component; furthermore, the influence of the levels and frequency ratio of the primaries are consistent with measurements. Analysis of the intracochlear response shows that the distortion component has the highest magnitude at all longitudinal locations for the 2f-f distortion product (DP) while the distortion component only dominates close to the DP best place in the case of the 2f-f DP. Decomposition of the intracochlear DPs into forward and reverse waves demonstrates that the 2f-f DP generates reverse waves for both the distortion and reflection components; however, a reverse wave is only generated for the reflection component in the case of the 2f-f DP. As in experiments in the gerbil, the group delay of the reflection component of the DPOAE is between 1× and 2× the forward group delay, which is consistent with the propagation of DP towards the stapes as slow reverse waves.
在这项工作中,使用沙鼠耳朵的三维计算模型来研究 2f-f 和 2f-f 失真产物耳声发射(DPOAE)的产生。为了预测失真和反射源,通过在外毛细胞特性中引入随机不均匀性来模拟耳蜗粗糙度。该模型用于模拟对各种初级刺激水平和频率比的双音刺激产生的 DPOAE。与已发表的实验一样,2f-f DPOAE 主要由失真分量主导,而 2f-f DPOAE 主要由反射分量主导;此外,主要水平和频率比的影响与测量结果一致。对 Cochlear 内响应的分析表明,在所有纵向位置,2f-f 失真产物(DP)的失真分量具有最大幅度,而在 2f-f DP 的情况下,只有在 DP 最佳位置附近才占主导地位。将 Cochlear 内 DP 分解为正向和反向波表明,2f-f DP 为失真和反射分量产生反向波;然而,在 2f-f DP 的情况下,只有反射分量产生反向波。与沙鼠中的实验一样,DPOAE 反射分量的群延迟在 1×到 2×正向群延迟之间,这与 DP 作为缓慢反向波向镫骨传播的情况一致。